null
SMILES: OC(=O)CCC(O)=O.COc1ccccc1C(=O)NC(=O)OC1CC2CCC(C1)N2C
InChI Key: InChIKey=HAMIDLUTHJEBEW-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
5-hydroxytryptamine receptor 3A/3B (Rattus norvegicus-RAT) | BDBM50455955 (CHEMBL411467) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | n/a | n/a | n/a | 17 | n/a | n/a | n/a | n/a | n/a |
Wyeth Research Curated by ChEMBL | Assay Description In vitro antagonism of the 5-HT-3 receptor determined by inhibition of 5-HT-induced depolarization of the isolated rat vagus nerve. | J Med Chem 35: 1515-20 (1992) BindingDB Entry DOI: 10.7270/Q24B32SK | |||||||||||
More data for this Ligand-Target Pair |