BDBM50455972 CHEMBL286676

SMILES: CN1CCC(CC1)OC(=O)NC(=O)c1cc(Cl)cc(Cl)c1

InChI Key: InChIKey=BNGKJFBMORIRIC-UHFFFAOYSA-N

Data: 1 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50455972   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor (Rattus norvegicus-RAT)	BDBM50455972 (CHEMBL286676) Show SMILES CN1CCC(CC1)OC(=O)NC(=O)c1cc(Cl)cc(Cl)c1 Show InChI InChI=1S/C14H16Cl2N2O3/c1-18-4-2-12(3-5-18)21-14(20)17-13(19)9-6-10(15)8-11(16)7-9/h6-8,12H,2-5H2,1H3,(H,17,19,20)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	n/a	126	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description In vitro antagonism of the 5-HT-3 receptor determined by inhibition of 5-HT-induced depolarization of the isolated rat vagus nerve.				J Med Chem 35: 1515-20 (1992) BindingDB Entry DOI: 10.7270/Q24B32SK
					More data for this Ligand-Target Pair