BDBM50556 4-[4-(2-thiophen-2-yl-4-quinazolinyl)-1-piperazinyl]phenol::4-[4-(2-thiophen-2-ylquinazolin-4-yl)piperazin-1-yl]phenol::4-[4-[2-(2-thienyl)quinazolin-4-yl]piperazino]phenol::MLS000774046::SMR000365148::cid_2469096

SMILES: Oc1ccc(cc1)N1CCN(CC1)c1nc(nc2ccccc12)-c1cccs1

InChI Key: InChIKey=WPLQOSMJLJTHBD-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50556   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Induced myeloid leukemia cell differentiation protein Mcl-1 (Homo sapiens (Human))	BDBM50556 (4-[4-(2-thiophen-2-yl-4-quinazolinyl)-1-piperaziny...) Show SMILES Oc1ccc(cc1)N1CCN(CC1)c1nc(nc2ccccc12)-c1cccs1 Show InChI InChI=1S/C22H20N4OS/c27-17-9-7-16(8-10-17)25-11-13-26(14-12-25)22-18-4-1-2-5-19(18)23-21(24-22)20-6-3-15-28-20/h1-10,15,27H,11-14H2	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
Emory University Molecular Libraries Screening Center Curated by PubChem BioAssay					Assay Description NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Nikolovska-Coleska, Univer...				PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q23X8539
					More data for this Ligand-Target Pair