null

SMILES: Cc1nc(COC(=O)c2cc(O)c3ccccc3c2O)cs1

InChI Key: InChIKey=FVZIEJLGRLIWGL-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50566   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Induced myeloid leukemia cell differentiation protein Mcl-1 (Homo sapiens (Human))	BDBM50566 ((2-methyl-1,3-thiazol-4-yl)methyl 1,4-bis(oxidanyl...) Show SMILES Cc1nc(COC(=O)c2cc(O)c3ccccc3c2O)cs1 Show InChI InChI=1S/C16H13NO4S/c1-9-17-10(8-22-9)7-21-16(20)13-6-14(18)11-4-2-3-5-12(11)15(13)19/h2-6,8,18-19H,7H2,1H3	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	4.84E+3	n/a	n/a	n/a	n/a	n/a	n/a
Emory University Molecular Libraries Screening Center Curated by PubChem BioAssay					Assay Description NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Nikolovska-Coleska, Univer...				PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q23X8539
					More data for this Ligand-Target Pair
Neutrophil cytosol factor 1 [S99G] (Homo sapiens (Human))	BDBM50566 ((2-methyl-1,3-thiazol-4-yl)methyl 1,4-bis(oxidanyl...) Show SMILES Cc1nc(COC(=O)c2cc(O)c3ccccc3c2O)cs1 Show InChI InChI=1S/C16H13NO4S/c1-9-17-10(8-22-9)7-21-16(20)13-6-14(18)11-4-2-3-5-12(11)15(13)19/h2-6,8,18-19H,7H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	7.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Emory University Molecular Libraries Screening Center Curated by PubChem BioAssay					Assay Description NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Susan Smith, Emory Univers...				PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2M90723
					More data for this Ligand-Target Pair
DNA damage-inducible transcript 3 protein (Mus musculus)	BDBM50566 ((2-methyl-1,3-thiazol-4-yl)methyl 1,4-bis(oxidanyl...) Show SMILES Cc1nc(COC(=O)c2cc(O)c3ccccc3c2O)cs1 Show InChI InChI=1S/C16H13NO4S/c1-9-17-10(8-22-9)7-21-16(20)13-6-14(18)11-4-2-3-5-12(11)15(13)19/h2-6,8,18-19H,7H2,1H3	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Emory University Molecular Libraries Screening Center Curated by PubChem BioAssay					Assay Description NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Dr. Randal Kaufman, Univer...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2PC30VZ
					More data for this Ligand-Target Pair
DNA damage-inducible transcript 3 protein (Mus musculus)	BDBM50566 ((2-methyl-1,3-thiazol-4-yl)methyl 1,4-bis(oxidanyl...) Show SMILES Cc1nc(COC(=O)c2cc(O)c3ccccc3c2O)cs1 Show InChI InChI=1S/C16H13NO4S/c1-9-17-10(8-22-9)7-21-16(20)13-6-14(18)11-4-2-3-5-12(11)15(13)19/h2-6,8,18-19H,7H2,1H3	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Emory University Molecular Libraries Screening Center Curated by PubChem BioAssay					Assay Description NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Dr. Randal Kaufman, Univer...				PubChem Bioassay (2011) BindingDB Entry DOI: 10.7270/Q28C9TQN
					More data for this Ligand-Target Pair
Hexokinase HKDC1 [W721R] (Homo sapiens (Human))	BDBM50566 ((2-methyl-1,3-thiazol-4-yl)methyl 1,4-bis(oxidanyl...) Show SMILES Cc1nc(COC(=O)c2cc(O)c3ccccc3c2O)cs1 Show InChI InChI=1S/C16H13NO4S/c1-9-17-10(8-22-9)7-21-16(20)13-6-14(18)11-4-2-3-5-12(11)15(13)19/h2-6,8,18-19H,7H2,1H3	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	1.21E+4	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2011) BindingDB Entry DOI: 10.7270/Q2W094D4
					More data for this Ligand-Target Pair
Glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase (Plasmodium falciparum 3D7)	BDBM50566 ((2-methyl-1,3-thiazol-4-yl)methyl 1,4-bis(oxidanyl...) Show SMILES Cc1nc(COC(=O)c2cc(O)c3ccccc3c2O)cs1 Show InChI InChI=1S/C16H13NO4S/c1-9-17-10(8-22-9)7-21-16(20)13-6-14(18)11-4-2-3-5-12(11)15(13)19/h2-6,8,18-19H,7H2,1H3	UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	>8.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego CA...				PubChem Bioassay (2011) BindingDB Entry DOI: 10.7270/Q23T9FQ1
					More data for this Ligand-Target Pair
Glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase (Plasmodium falciparum 3D7)	BDBM50566 ((2-methyl-1,3-thiazol-4-yl)methyl 1,4-bis(oxidanyl...) Show SMILES Cc1nc(COC(=O)c2cc(O)c3ccccc3c2O)cs1 Show InChI InChI=1S/C16H13NO4S/c1-9-17-10(8-22-9)7-21-16(20)13-6-14(18)11-4-2-3-5-12(11)15(13)19/h2-6,8,18-19H,7H2,1H3	UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	3.52E+3	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego CA...				PubChem Bioassay (2011) BindingDB Entry DOI: 10.7270/Q2ZS2TZG
					More data for this Ligand-Target Pair
Glucose-6-phosphate 1-dehydrogenase (Homo sapiens (Human))	BDBM50566 ((2-methyl-1,3-thiazol-4-yl)methyl 1,4-bis(oxidanyl...) Show SMILES Cc1nc(COC(=O)c2cc(O)c3ccccc3c2O)cs1 Show InChI InChI=1S/C16H13NO4S/c1-9-17-10(8-22-9)7-21-16(20)13-6-14(18)11-4-2-3-5-12(11)15(13)19/h2-6,8,18-19H,7H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	>8.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego CA...				PubChem Bioassay (2011) BindingDB Entry DOI: 10.7270/Q2V12389
					More data for this Ligand-Target Pair
Hexokinase HKDC1 [W721R] (Homo sapiens (Human))	BDBM50566 ((2-methyl-1,3-thiazol-4-yl)methyl 1,4-bis(oxidanyl...) Show SMILES Cc1nc(COC(=O)c2cc(O)c3ccccc3c2O)cs1 Show InChI InChI=1S/C16H13NO4S/c1-9-17-10(8-22-9)7-21-16(20)13-6-14(18)11-4-2-3-5-12(11)15(13)19/h2-6,8,18-19H,7H2,1H3	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2011) BindingDB Entry DOI: 10.7270/Q23F4N3R
					More data for this Ligand-Target Pair
Glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase (Plasmodium falciparum 3D7)	BDBM50566 ((2-methyl-1,3-thiazol-4-yl)methyl 1,4-bis(oxidanyl...) Show SMILES Cc1nc(COC(=O)c2cc(O)c3ccccc3c2O)cs1 Show InChI InChI=1S/C16H13NO4S/c1-9-17-10(8-22-9)7-21-16(20)13-6-14(18)11-4-2-3-5-12(11)15(13)19/h2-6,8,18-19H,7H2,1H3	UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	>8.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego CA...				PubChem Bioassay (2011) BindingDB Entry DOI: 10.7270/Q27H1H3W
					More data for this Ligand-Target Pair
X-box-binding protein 1 (Homo sapiens (Human))	BDBM50566 ((2-methyl-1,3-thiazol-4-yl)methyl 1,4-bis(oxidanyl...) Show SMILES Cc1nc(COC(=O)c2cc(O)c3ccccc3c2O)cs1 Show InChI InChI=1S/C16H13NO4S/c1-9-17-10(8-22-9)7-21-16(20)13-6-14(18)11-4-2-3-5-12(11)15(13)19/h2-6,8,18-19H,7H2,1H3	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	9.28E+3	n/a	n/a	n/a	n/a	n/a	n/a
Emory University Molecular Libraries Screening Center Curated by PubChem BioAssay					Assay Description NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Dr. Randal Kaufman, Univer...				PubChem Bioassay (2011) BindingDB Entry DOI: 10.7270/Q2NK3CGB
					More data for this Ligand-Target Pair