BDBM52401 4-[(E)-2-(1,3-benzothiazol-2-yl)ethenyl]-N,N-dimethyl-aniline::4-[(E)-2-(1,3-benzothiazol-2-yl)ethenyl]-N,N-dimethylaniline::4-[2-(1,3-benzothiazol-2-yl)vinyl]-N,N-dimethylaniline::CHEMBL565657::MLS000573782::SMR000184633::[4-[(E)-2-(1,3-benzothiazol-2-yl)vinyl]phenyl]-dimethyl-amine::cid_5378081

SMILES: CN(C)c1ccc(\C=C\c2nc3ccccc3s2)cc1

InChI Key: InChIKey=MVMOMSLTZMMLJR-FMIVXFBMSA-N

Data: 1 KI  3 IC50  2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 52401   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Amyloid-beta precursor protein (Homo sapiens (Human))	BDBM52401 (4-[(E)-2-(1,3-benzothiazol-2-yl)ethenyl]-N,N-dimet...) Show SMILES CN(C)c1ccc(\C=C\c2nc3ccccc3s2)cc1 Show InChI InChI=1S/C17H16N2S/c1-19(2)14-10-7-13(8-11-14)9-12-17-18-15-5-3-4-6-16(15)20-17/h3-12H,1-2H3/b12-9+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	2.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Binding affinity to Beta amyloid aggregates in Alzheimer's disease patient brain by competitive binding assay				J Med Chem 53: 933-41 (2010) Article DOI: 10.1021/jm901039z BindingDB Entry DOI: 10.7270/Q2RX9FW6
					More data for this Ligand-Target Pair
Zinc finger protein mex-5 (Caenorhabditis elegans)	BDBM52401 (4-[(E)-2-(1,3-benzothiazol-2-yl)ethenyl]-N,N-dimet...) Show SMILES CN(C)c1ccc(\C=C\c2nc3ccccc3s2)cc1 Show InChI InChI=1S/C17H16N2S/c1-19(2)14-10-7-13(8-11-14)9-12-17-18-15-5-3-4-6-16(15)20-17/h3-12H,1-2H3/b12-9+	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PCBioAssay	n/a	n/a	n/a	n/a	3.00E+5	n/a	n/a	n/a	n/a
Broad Institute Curated by PubChem BioAssay					Assay Description Broad Institute: MLPCN maternal gene expression Project ID: 2024 Keywords: Zinc finger, C. elegans, maternal gene expression, RNA-protein interac...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2D798VP
					More data for this Ligand-Target Pair
Nuclear receptor coactivator 1 (Homo sapiens (Human))	BDBM52401 (4-[(E)-2-(1,3-benzothiazol-2-yl)ethenyl]-N,N-dimet...) Show SMILES CN(C)c1ccc(\C=C\c2nc3ccccc3s2)cc1 Show InChI InChI=1S/C17H16N2S/c1-19(2)14-10-7-13(8-11-14)9-12-17-18-15-5-3-4-6-16(15)20-17/h3-12H,1-2H3/b12-9+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PCBioAssay	n/a	n/a	2.04E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay					Assay Description Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...				PubChem Bioassay (2012) BindingDB Entry DOI: 10.7270/Q2794387
					More data for this Ligand-Target Pair
Insulin receptor (Homo sapiens (Human))	BDBM52401 (4-[(E)-2-(1,3-benzothiazol-2-yl)ethenyl]-N,N-dimet...) Show SMILES CN(C)c1ccc(\C=C\c2nc3ccccc3s2)cc1 Show InChI InChI=1S/C17H16N2S/c1-19(2)14-10-7-13(8-11-14)9-12-17-18-15-5-3-4-6-16(15)20-17/h3-12H,1-2H3/b12-9+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Ohio State University College of Medicine Curated by ChEMBL					Assay Description Displacement of thioflavin T from insulin receptor by thioflavin-T fluorescent dye assay				Bioorg Med Chem 20: 1434-41 (2012) Article DOI: 10.1016/j.bmc.2011.12.062 BindingDB Entry DOI: 10.7270/Q2M32W7W
					More data for this Ligand-Target Pair
POsterior Segregation (Caenorhabditis elegans)	BDBM52401 (4-[(E)-2-(1,3-benzothiazol-2-yl)ethenyl]-N,N-dimet...) Show SMILES CN(C)c1ccc(\C=C\c2nc3ccccc3s2)cc1 Show InChI InChI=1S/C17H16N2S/c1-19(2)14-10-7-13(8-11-14)9-12-17-18-15-5-3-4-6-16(15)20-17/h3-12H,1-2H3/b12-9+	PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PCBioAssay	n/a	n/a	n/a	n/a	3.00E+5	n/a	n/a	n/a	n/a
Broad Institute Curated by PubChem BioAssay					Assay Description Broad Institute: MLPCN maternal gene expression Project ID: 2024 Keywords: Zinc finger, C. elegans, maternal gene expression, RNA-protein interac...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q28G8J4C
					More data for this Ligand-Target Pair
Nuclear receptor coactivator 3 (Homo sapiens (Human))	BDBM52401 (4-[(E)-2-(1,3-benzothiazol-2-yl)ethenyl]-N,N-dimet...) Show SMILES CN(C)c1ccc(\C=C\c2nc3ccccc3s2)cc1 Show InChI InChI=1S/C17H16N2S/c1-19(2)14-10-7-13(8-11-14)9-12-17-18-15-5-3-4-6-16(15)20-17/h3-12H,1-2H3/b12-9+	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PCBioAssay	n/a	n/a	>148	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay					Assay Description Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...				PubChem Bioassay (2012) BindingDB Entry DOI: 10.7270/Q2C24V0K
					More data for this Ligand-Target Pair