BDBM53725 MLS000035506::N-[(5Z)-5-(4,5-dimethoxy-2-nitro-benzylidene)-4-keto-2-thiazolin-2-yl]benzenesulfonamide::N-[(5Z)-5-[(4,5-dimethoxy-2-nitro-phenyl)methylidene]-4-oxidanylidene-1,3-thiazol-2-yl]benzenesulfonamide::N-[(5Z)-5-[(4,5-dimethoxy-2-nitrophenyl)methylidene]-4-oxo-1,3-thiazol-2-yl]benzenesulfonamide::N-[(5Z)-5-[(4,5-dimethoxy-2-nitrophenyl)methylidene]-4-oxo-2-thiazolyl]benzenesulfonamide::N-[5-(4,5-Dimethoxy-2-nitro-benzylidene)-4-oxo-thiazolidin-2-ylidene]-benzenesulfonamide::SMR000123103::cid_1912687
SMILES: COc1cc(\C=C2/SC(NS(=O)(=O)c3ccccc3)=NC2=O)c(cc1OC)[N+]([O-])=O
InChI Key: InChIKey=DXPFGKPJCBOMGO-SXGWCWSVSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Zinc aminopeptidase (Plasmodium falciparum (isolate FcB1 / Columbia)) | BDBM53725 (MLS000035506 | N-[(5Z)-5-(4,5-dimethoxy-2-nitro-be...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | PCBioAssay | n/a | n/a | 2.55E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
SRMLSC Curated by PubChem BioAssay | Assay Description Southern Research Molecular Libraries Screening Center (SRMLSC) Southern Research Institute (Birmingham, Alabama) NIH Molecular Libraries Screening... | PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q27H1H0J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Homo sapiens huntingtin (HTT), mRNA (Homo sapiens (Human)) | BDBM53725 (MLS000035506 | N-[(5Z)-5-(4,5-dimethoxy-2-nitro-be...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | PCBioAssay | n/a | n/a | 848 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay | PubChem Bioassay (2013) BindingDB Entry DOI: 10.7270/Q2N58K09 | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
streptokinase A precursor (Streptococcus pyogenes M1 GAS) | BDBM53725 (MLS000035506 | N-[(5Z)-5-(4,5-dimethoxy-2-nitro-be...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | PCBioAssay | n/a | n/a | n/a | n/a | 1.50E+5 | n/a | n/a | n/a | n/a |
Broad Institute Curated by PubChem BioAssay | Assay Description Keywords: Group A streptococcus, GAS, streptokinase, expression, virulence, inhibition, dose response, EC50 Assay Overview: The goal of this assa... | PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2736PBV | |||||||||||
More data for this Ligand-Target Pair |