BDBM54188 1-(3-methylphenyl)-3-[(Z)-(2-oxidanylidene-1-prop-2-enyl-indol-3-ylidene)amino]thiourea::1-(3-methylphenyl)-3-[(Z)-(2-oxo-1-prop-2-enyl-3-indolylidene)amino]thiourea::1-(3-methylphenyl)-3-[(Z)-(2-oxo-1-prop-2-enylindol-3-ylidene)amino]thiourea::1-[(Z)-(1-allyl-2-keto-indolin-3-ylidene)amino]-3-(m-tolyl)thiourea::MLS000522059::SMR000132467::cid_6296094

SMILES: Cc1cccc(NC(=S)NN=C2C(=O)N(CC=C)c3ccccc23)c1

InChI Key: InChIKey=MXOMWRVTXOTHJQ-UHFFFAOYSA-N

Data: 4 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 54188   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
nucleotide-binding oligomerization domain containing 2 (Homo sapiens (Human))	BDBM54188 (1-(3-methylphenyl)-3-[(Z)-(2-oxidanylidene-1-prop-...) Show SMILES Cc1cccc(NC(=S)NN=C2C(=O)N(CC=C)c3ccccc23)c1 |w:10.9| Show InChI InChI=1S/C19H18N4OS/c1-3-11-23-16-10-5-4-9-15(16)17(18(23)24)21-22-19(25)20-14-8-6-7-13(2)12-14/h3-10,12H,1,11H2,2H3,(H2,20,22,25)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	1.18E+3	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q23R0R8T
					More data for this Ligand-Target Pair
nucleotide-binding oligomerization domain containing 1 (Homo sapiens (Human))	BDBM54188 (1-(3-methylphenyl)-3-[(Z)-(2-oxidanylidene-1-prop-...) Show SMILES Cc1cccc(NC(=S)NN=C2C(=O)N(CC=C)c3ccccc23)c1 |w:10.9| Show InChI InChI=1S/C19H18N4OS/c1-3-11-23-16-10-5-4-9-15(16)17(18(23)24)21-22-19(25)20-14-8-6-7-13(2)12-14/h3-10,12H,1,11H2,2H3,(H2,20,22,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	1.09E+3	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2CN72C0
					More data for this Ligand-Target Pair
Protein Wnt-3a (Mus musculus)	BDBM54188 (1-(3-methylphenyl)-3-[(Z)-(2-oxidanylidene-1-prop-...) Show SMILES Cc1cccc(NC(=S)NN=C2C(=O)N(CC=C)c3ccccc23)c1 |w:10.9| Show InChI InChI=1S/C19H18N4OS/c1-3-11-23-16-10-5-4-9-15(16)17(18(23)24)21-22-19(25)20-14-8-6-7-13(2)12-14/h3-10,12H,1,11H2,2H3,(H2,20,22,25)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	2.92E+4	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay									PubChem Bioassay (2012) BindingDB Entry DOI: 10.7270/Q25B012X
					More data for this Ligand-Target Pair
Zinc finger protein GLI1 (Mus musculus)	BDBM54188 (1-(3-methylphenyl)-3-[(Z)-(2-oxidanylidene-1-prop-...) Show SMILES Cc1cccc(NC(=S)NN=C2C(=O)N(CC=C)c3ccccc23)c1 |w:10.9| Show InChI InChI=1S/C19H18N4OS/c1-3-11-23-16-10-5-4-9-15(16)17(18(23)24)21-22-19(25)20-14-8-6-7-13(2)12-14/h3-10,12H,1,11H2,2H3,(H2,20,22,25)	PDB MMDB B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	8.58E+3	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2012) BindingDB Entry DOI: 10.7270/Q2862F26
					More data for this Ligand-Target Pair
Tumor necrosis factor (Homo sapiens (Human))	BDBM54188 (1-(3-methylphenyl)-3-[(Z)-(2-oxidanylidene-1-prop-...) Show SMILES Cc1cccc(NC(=S)NN=C2C(=O)N(CC=C)c3ccccc23)c1 |w:10.9| Show InChI InChI=1S/C19H18N4OS/c1-3-11-23-16-10-5-4-9-15(16)17(18(23)24)21-22-19(25)20-14-8-6-7-13(2)12-14/h3-10,12H,1,11H2,2H3,(H2,20,22,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	2.97E+3	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q25M6443
					More data for this Ligand-Target Pair