BDBM54189 1-(3-methoxyphenyl)-3-[(Z)-(2-oxidanylidene-1-prop-2-enyl-indol-3-ylidene)amino]thiourea::1-(3-methoxyphenyl)-3-[(Z)-(2-oxo-1-prop-2-enyl-3-indolylidene)amino]thiourea::1-(3-methoxyphenyl)-3-[(Z)-(2-oxo-1-prop-2-enylindol-3-ylidene)amino]thiourea::1-[(Z)-(1-allyl-2-keto-indolin-3-ylidene)amino]-3-(3-methoxyphenyl)thiourea::MLS000522061::SMR000132469::cid_6296179

SMILES: COc1cccc(NC(=S)NN=C2C(=O)N(CC=C)c3ccccc23)c1

InChI Key: InChIKey=MNJDBDAVHRAXFT-UHFFFAOYSA-N

Data: 2 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 54189   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
nucleotide-binding oligomerization domain containing 2 (Homo sapiens (Human))	BDBM54189 (1-(3-methoxyphenyl)-3-[(Z)-(2-oxidanylidene-1-prop...) Show SMILES COc1cccc(NC(=S)NN=C2C(=O)N(CC=C)c3ccccc23)c1 |w:11.10| Show InChI InChI=1S/C19H18N4O2S/c1-3-11-23-16-10-5-4-9-15(16)17(18(23)24)21-22-19(26)20-13-7-6-8-14(12-13)25-2/h3-10,12H,1,11H2,2H3,(H2,20,22,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	1.76E+3	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q23R0R8T
					More data for this Ligand-Target Pair
Tumor necrosis factor (Homo sapiens (Human))	BDBM54189 (1-(3-methoxyphenyl)-3-[(Z)-(2-oxidanylidene-1-prop...) Show SMILES COc1cccc(NC(=S)NN=C2C(=O)N(CC=C)c3ccccc23)c1 |w:11.10| Show InChI InChI=1S/C19H18N4O2S/c1-3-11-23-16-10-5-4-9-15(16)17(18(23)24)21-22-19(26)20-13-7-6-8-14(12-13)25-2/h3-10,12H,1,11H2,2H3,(H2,20,22,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	3.41E+3	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q25M6443
					More data for this Ligand-Target Pair
nucleotide-binding oligomerization domain containing 1 (Homo sapiens (Human))	BDBM54189 (1-(3-methoxyphenyl)-3-[(Z)-(2-oxidanylidene-1-prop...) Show SMILES COc1cccc(NC(=S)NN=C2C(=O)N(CC=C)c3ccccc23)c1 |w:11.10| Show InChI InChI=1S/C19H18N4O2S/c1-3-11-23-16-10-5-4-9-15(16)17(18(23)24)21-22-19(26)20-13-7-6-8-14(12-13)25-2/h3-10,12H,1,11H2,2H3,(H2,20,22,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2CN72C0
					More data for this Ligand-Target Pair