BDBM54667 4-[3-(4-methoxyphenyl)-5-[2-(trifluoromethyl)phenyl]-3,4-dihydropyrazol-2-yl]benzenesulfonamide::4-[5-(4-methoxyphenyl)-3-[2-(trifluoromethyl)phenyl]-2-pyrazolin-1-yl]benzenesulfonamide::KUC103474N::cid_44216837

SMILES: COc1ccc(cc1)C1CC(=NN1c1ccc(cc1)S(N)(=O)=O)c1ccccc1C(F)(F)F

InChI Key: InChIKey=WORFZZFIGKGOGO-UHFFFAOYSA-N

Data: 9 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 54667   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ras-related protein Rab-2A. (Canis lupus familiaris)	BDBM54667 (4-[3-(4-methoxyphenyl)-5-[2-(trifluoromethyl)pheny...) Show SMILES COc1ccc(cc1)C1CC(=NN1c1ccc(cc1)S(N)(=O)=O)c1ccccc1C(F)(F)F |c:11| Show InChI InChI=1S/C23H20F3N3O3S/c1-32-17-10-6-15(7-11-17)22-14-21(19-4-2-3-5-20(19)23(24,25)26)28-29(22)16-8-12-18(13-9-16)33(27,30)31/h2-13,22H,14H2,1H3,(H2,27,30,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a
NMMLSC Curated by PubChem BioAssay					Assay Description University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...				PubChem Bioassay (2016) BindingDB Entry DOI: 10.7270/Q2ZW1JC6
					More data for this Ligand-Target Pair
ras protein (Homo sapiens (Human))	BDBM54667 (4-[3-(4-methoxyphenyl)-5-[2-(trifluoromethyl)pheny...) Show SMILES COc1ccc(cc1)C1CC(=NN1c1ccc(cc1)S(N)(=O)=O)c1ccccc1C(F)(F)F |c:11| Show InChI InChI=1S/C23H20F3N3O3S/c1-32-17-10-6-15(7-11-17)22-14-21(19-4-2-3-5-20(19)23(24,25)26)28-29(22)16-8-12-18(13-9-16)33(27,30)31/h2-13,22H,14H2,1H3,(H2,27,30,31)	GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a
NMMLSC Curated by PubChem BioAssay					Assay Description University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2KK9971
					More data for this Ligand-Target Pair
Ras-related C3 botulinum toxin substrate 1 (Mus musculus)	BDBM54667 (4-[3-(4-methoxyphenyl)-5-[2-(trifluoromethyl)pheny...) Show SMILES COc1ccc(cc1)C1CC(=NN1c1ccc(cc1)S(N)(=O)=O)c1ccccc1C(F)(F)F |c:11| Show InChI InChI=1S/C23H20F3N3O3S/c1-32-17-10-6-15(7-11-17)22-14-21(19-4-2-3-5-20(19)23(24,25)26)28-29(22)16-8-12-18(13-9-16)33(27,30)31/h2-13,22H,14H2,1H3,(H2,27,30,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a
NMMLSC Curated by PubChem BioAssay					Assay Description University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2B56H55
					More data for this Ligand-Target Pair
ras protein (Homo sapiens (Human))	BDBM54667 (4-[3-(4-methoxyphenyl)-5-[2-(trifluoromethyl)pheny...) Show SMILES COc1ccc(cc1)C1CC(=NN1c1ccc(cc1)S(N)(=O)=O)c1ccccc1C(F)(F)F |c:11| Show InChI InChI=1S/C23H20F3N3O3S/c1-32-17-10-6-15(7-11-17)22-14-21(19-4-2-3-5-20(19)23(24,25)26)28-29(22)16-8-12-18(13-9-16)33(27,30)31/h2-13,22H,14H2,1H3,(H2,27,30,31)	GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a
NMMLSC Curated by PubChem BioAssay					Assay Description University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q22N50Q3
					More data for this Ligand-Target Pair
Candida albicans strain ATCC 10261 multidrug efflux pump (MDR1) gene, MDR1-A allele, complete cds (Candida albicans)	BDBM54667 (4-[3-(4-methoxyphenyl)-5-[2-(trifluoromethyl)pheny...) Show SMILES COc1ccc(cc1)C1CC(=NN1c1ccc(cc1)S(N)(=O)=O)c1ccccc1C(F)(F)F |c:11| Show InChI InChI=1S/C23H20F3N3O3S/c1-32-17-10-6-15(7-11-17)22-14-21(19-4-2-3-5-20(19)23(24,25)26)28-29(22)16-8-12-18(13-9-16)33(27,30)31/h2-13,22H,14H2,1H3,(H2,27,30,31)	UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	2.26E+4	n/a	n/a	n/a	n/a
NMMLSC Curated by PubChem BioAssay					Assay Description UNMCMD Assay Overview: Assay Support: 1 R03 MH087406-01A1 Project Title: Identification of broad-spectrum antifungal efflux pump inhibitors ...				PubChem Bioassay (2011) BindingDB Entry DOI: 10.7270/Q20V8B9F
					More data for this Ligand-Target Pair
cell division cycle 42 (GTP binding protein, 25kDa) (Homo sapiens (Human))	BDBM54667 (4-[3-(4-methoxyphenyl)-5-[2-(trifluoromethyl)pheny...) Show SMILES COc1ccc(cc1)C1CC(=NN1c1ccc(cc1)S(N)(=O)=O)c1ccccc1C(F)(F)F |c:11| Show InChI InChI=1S/C23H20F3N3O3S/c1-32-17-10-6-15(7-11-17)22-14-21(19-4-2-3-5-20(19)23(24,25)26)28-29(22)16-8-12-18(13-9-16)33(27,30)31/h2-13,22H,14H2,1H3,(H2,27,30,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a
NMMLSC Curated by PubChem BioAssay					Assay Description University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2QJ7FRJ
					More data for this Ligand-Target Pair
cell division cycle 42 (GTP binding protein, 25kDa) (Homo sapiens (Human))	BDBM54667 (4-[3-(4-methoxyphenyl)-5-[2-(trifluoromethyl)pheny...) Show SMILES COc1ccc(cc1)C1CC(=NN1c1ccc(cc1)S(N)(=O)=O)c1ccccc1C(F)(F)F |c:11| Show InChI InChI=1S/C23H20F3N3O3S/c1-32-17-10-6-15(7-11-17)22-14-21(19-4-2-3-5-20(19)23(24,25)26)28-29(22)16-8-12-18(13-9-16)33(27,30)31/h2-13,22H,14H2,1H3,(H2,27,30,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a
NMMLSC Curated by PubChem BioAssay					Assay Description University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2G15Z8C
					More data for this Ligand-Target Pair
GTP-binding protein (rab7) (Canis lupus familiaris)	BDBM54667 (4-[3-(4-methoxyphenyl)-5-[2-(trifluoromethyl)pheny...) Show SMILES COc1ccc(cc1)C1CC(=NN1c1ccc(cc1)S(N)(=O)=O)c1ccccc1C(F)(F)F |c:11| Show InChI InChI=1S/C23H20F3N3O3S/c1-32-17-10-6-15(7-11-17)22-14-21(19-4-2-3-5-20(19)23(24,25)26)28-29(22)16-8-12-18(13-9-16)33(27,30)31/h2-13,22H,14H2,1H3,(H2,27,30,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a
NMMLSC Curated by PubChem BioAssay					Assay Description University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2MK6B9H
					More data for this Ligand-Target Pair
Ras-related C3 botulinum toxin substrate 1 (Mus musculus)	BDBM54667 (4-[3-(4-methoxyphenyl)-5-[2-(trifluoromethyl)pheny...) Show SMILES COc1ccc(cc1)C1CC(=NN1c1ccc(cc1)S(N)(=O)=O)c1ccccc1C(F)(F)F |c:11| Show InChI InChI=1S/C23H20F3N3O3S/c1-32-17-10-6-15(7-11-17)22-14-21(19-4-2-3-5-20(19)23(24,25)26)28-29(22)16-8-12-18(13-9-16)33(27,30)31/h2-13,22H,14H2,1H3,(H2,27,30,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a
NMMLSC Curated by PubChem BioAssay					Assay Description University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2959G0B
					More data for this Ligand-Target Pair