BDBM55083 N-[3-chloranyl-4-[(2-chlorophenyl)carbonylamino]phenyl]pyridine-2-carboxamide::N-[3-chloro-4-[(2-chlorobenzoyl)amino]phenyl]picolinamide::N-[3-chloro-4-[(2-chlorobenzoyl)amino]phenyl]pyridine-2-carboxamide::N-[3-chloro-4-[[(2-chlorophenyl)-oxomethyl]amino]phenyl]-2-pyridinecarboxamide::VU0366037-2::cid_46869941

SMILES: Clc1ccccc1C(=O)Nc1ccc(NC(=O)c2ccccn2)cc1Cl

InChI Key: InChIKey=MTELUFOIWGSEFF-UHFFFAOYSA-N

Data: 4 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 55083   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 4 (mGluR4) (Homo sapiens (Human))	BDBM55083 (N-[3-chloranyl-4-[(2-chlorophenyl)carbonylamino]ph...) Show SMILES Clc1ccccc1C(=O)Nc1ccc(NC(=O)c2ccccn2)cc1Cl Show InChI InChI=1S/C19H13Cl2N3O2/c20-14-6-2-1-5-13(14)18(25)24-16-9-8-12(11-15(16)21)23-19(26)17-7-3-4-10-22-17/h1-11H,(H,23,26)(H,24,25)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	529	n/a	n/a	n/a	n/a
Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters Curated by PubChem BioAssay					Assay Description Assay Provider: Colleen Niswender Assay Provider Affiliation: Vanderbilt University The primary pathophysiological change giving rise to the symptoms...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2VT1QHF
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (mGlu4) (Rattus norvegicus (Rat))	BDBM55083 (N-[3-chloranyl-4-[(2-chlorophenyl)carbonylamino]ph...) Show SMILES Clc1ccccc1C(=O)Nc1ccc(NC(=O)c2ccccn2)cc1Cl Show InChI InChI=1S/C19H13Cl2N3O2/c20-14-6-2-1-5-13(14)18(25)24-16-9-8-12(11-15(16)21)23-19(26)17-7-3-4-10-22-17/h1-11H,(H,23,26)(H,24,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	570	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Positive allosteric modulation of rat mGluR4 expressed in CHO cells coexpressing Gqi5 assessed as calcium mobilization				J Med Chem 54: 1106-10 (2011) Article DOI: 10.1021/jm101271s BindingDB Entry DOI: 10.7270/Q27P90C1
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (mGluR4) (Homo sapiens (Human))	BDBM55083 (N-[3-chloranyl-4-[(2-chlorophenyl)carbonylamino]ph...) Show SMILES Clc1ccccc1C(=O)Nc1ccc(NC(=O)c2ccccn2)cc1Cl Show InChI InChI=1S/C19H13Cl2N3O2/c20-14-6-2-1-5-13(14)18(25)24-16-9-8-12(11-15(16)21)23-19(26)17-7-3-4-10-22-17/h1-11H,(H,23,26)(H,24,25)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	517	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Positive allosteric modulation of human mGluR4 expressed in CHO cells coexpressing Gqi5 assessed as calcium mobilization				J Med Chem 54: 1106-10 (2011) Article DOI: 10.1021/jm101271s BindingDB Entry DOI: 10.7270/Q27P90C1
					More data for this Ligand-Target Pair
glutamate receptor, metabotropic 4 precursor (Rattus norvegicus)	BDBM55083 (N-[3-chloranyl-4-[(2-chlorophenyl)carbonylamino]ph...) Show SMILES Clc1ccccc1C(=O)Nc1ccc(NC(=O)c2ccccn2)cc1Cl Show InChI InChI=1S/C19H13Cl2N3O2/c20-14-6-2-1-5-13(14)18(25)24-16-9-8-12(11-15(16)21)23-19(26)17-7-3-4-10-22-17/h1-11H,(H,23,26)(H,24,25)	PDB KEGG GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	750	n/a	n/a	n/a	n/a
Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters Curated by PubChem BioAssay					Assay Description Assay Provider: Colleen Niswender Assay Provider Affiliation: Vanderbilt University The primary pathophysiological change giving rise to the symptoms...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2DR2SWV
					More data for this Ligand-Target Pair