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SMILES: COc1ccc(NC(=O)c2c[nH]n3c2nc(cc3=O)C2CCN(CC2)C(=O)OC(C)(C)C)cc1Cl

InChI Key: InChIKey=CLCXJBMOHJFHMD-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 57891   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Streptokinase A


(Streptococcus pyogenes M1 GAS)		BDBM57891
PNG
(4-[3-[(3-chloro-4-methoxy-phenyl)carbamoyl]-7-keto...)
Show SMILES COc1ccc(NC(=O)c2c[nH]n3c2nc(cc3=O)C2CCN(CC2)C(=O)OC(C)(C)C)cc1Cl
Show InChI InChI=1S/C24H28ClN5O5/c1-24(2,3)35-23(33)29-9-7-14(8-10-29)18-12-20(31)30-21(28-18)16(13-26-30)22(32)27-15-5-6-19(34-4)17(25)11-15/h5-6,11-14,26H,7-10H2,1-4H3,(H,27,32)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars
PCBioAssay
n/an/an/an/a 1.50E+5n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: Group A streptococcus, GAS, streptokinase, expression, virulence, inhibition, dose response, EC50 Assay Overview: The goal of this assa...

PubChem Bioassay (2009)


BindingDB Entry DOI: 10.7270/Q2736PBV
More data for this
Ligand-Target Pair
G-protein coupled receptor 55


(Homo sapiens (Human))		BDBM57891
PNG
(4-[3-[(3-chloro-4-methoxy-phenyl)carbamoyl]-7-keto...)
Show SMILES COc1ccc(NC(=O)c2c[nH]n3c2nc(cc3=O)C2CCN(CC2)C(=O)OC(C)(C)C)cc1Cl
Show InChI InChI=1S/C24H28ClN5O5/c1-24(2,3)35-23(33)29-9-7-14(8-10-29)18-12-20(31)30-21(28-18)16(13-26-30)22(32)27-15-5-6-19(34-4)17(25)11-15/h5-6,11-14,26H,7-10H2,1-4H3,(H,27,32)
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars
PCBioAssay
n/an/a 500n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...

PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2348HSG
More data for this
Ligand-Target Pair