BDBM58019 5-methyl-N-(4-pyridin-2-yl-1,3-thiazol-2-yl)furan-2-carboxamide::5-methyl-N-[4-(2-pyridinyl)-2-thiazolyl]-2-furancarboxamide::5-methyl-N-[4-(2-pyridyl)thiazol-2-yl]-2-furamide::MLS001010722::SMR000385065::cid_2466262

SMILES: Cc1ccc(o1)C(=O)Nc1nc(cs1)-c1ccccn1

InChI Key: InChIKey=JBHGMEXQQLQBSO-UHFFFAOYSA-N

Data: 4 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 58019   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
streptokinase A precursor (Streptococcus pyogenes M1 GAS)	BDBM58019 (5-methyl-N-(4-pyridin-2-yl-1,3-thiazol-2-yl)furan-...) Show SMILES Cc1ccc(o1)C(=O)Nc1nc(cs1)-c1ccccn1 Show InChI InChI=1S/C14H11N3O2S/c1-9-5-6-12(19-9)13(18)17-14-16-11(8-20-14)10-4-2-3-7-15-10/h2-8H,1H3,(H,16,17,18)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	1.50E+5	n/a	n/a	n/a	n/a
Broad Institute Curated by PubChem BioAssay					Assay Description Keywords: Group A streptococcus, GAS, streptokinase, expression, virulence, inhibition, dose response, EC50 Assay Overview: The goal of this assa...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2736PBV
					More data for this Ligand-Target Pair
RPL19A (Saccharomyces cerevisiae)	BDBM58019 (5-methyl-N-(4-pyridin-2-yl-1,3-thiazol-2-yl)furan-...) Show SMILES Cc1ccc(o1)C(=O)Nc1nc(cs1)-c1ccccn1 Show InChI InChI=1S/C14H11N3O2S/c1-9-5-6-12(19-9)13(18)17-14-16-11(8-20-14)10-4-2-3-7-15-10/h2-8H,1H3,(H,16,17,18)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	3.83E+4	n/a	n/a	n/a	n/a
NMMLSC Curated by PubChem BioAssay					Assay Description University of New Mexico Assay Overview: Assay Support: 1R03 MH086450-01 Project Title: Chemical Screen of TOR pathway GFP fusion proteins in S. ...				PubChem Bioassay (2011) BindingDB Entry DOI: 10.7270/Q2H70D87
					More data for this Ligand-Target Pair
Agp1p (Saccharomyces cerevisiae S288c)	BDBM58019 (5-methyl-N-(4-pyridin-2-yl-1,3-thiazol-2-yl)furan-...) Show SMILES Cc1ccc(o1)C(=O)Nc1nc(cs1)-c1ccccn1 Show InChI InChI=1S/C14H11N3O2S/c1-9-5-6-12(19-9)13(18)17-14-16-11(8-20-14)10-4-2-3-7-15-10/h2-8H,1H3,(H,16,17,18)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	7.75E+5	n/a	n/a	n/a	n/a
NMMLSC Curated by PubChem BioAssay					Assay Description University of New Mexico Assay Overview: Assay Support: 1R03 MH086450-01 Project Title: Chemical Screen of TOR pathway GFP fusion proteins in S. ...				PubChem Bioassay (2011) BindingDB Entry DOI: 10.7270/Q28P5XZM
					More data for this Ligand-Target Pair
citrate synthase 2 (Saccharomyces cerevisiae)	BDBM58019 (5-methyl-N-(4-pyridin-2-yl-1,3-thiazol-2-yl)furan-...) Show SMILES Cc1ccc(o1)C(=O)Nc1nc(cs1)-c1ccccn1 Show InChI InChI=1S/C14H11N3O2S/c1-9-5-6-12(19-9)13(18)17-14-16-11(8-20-14)10-4-2-3-7-15-10/h2-8H,1H3,(H,16,17,18)	GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	3.68E+6	n/a	n/a	n/a	n/a
NMMLSC Curated by PubChem BioAssay					Assay Description University of New Mexico Assay Overview: Assay Support: 1R03 MH086450-01 Project Title: Chemical Screen of TOR pathway GFP fusion proteins in S. ...				PubChem Bioassay (2011) BindingDB Entry DOI: 10.7270/Q2QN6575
					More data for this Ligand-Target Pair