BDBM58076 (5-Isopropyl-2-methyl-3-phenyl-pyrazolo[1,5-a]pyrimidin-7-yl)-pyridin-2-ylmethyl-amine::(5-isopropyl-2-methyl-3-phenyl-pyrazolo[1,5-a]pyrimidin-7-yl)-(2-pyridylmethyl)amine::2-methyl-3-phenyl-5-propan-2-yl-N-(2-pyridinylmethyl)-7-pyrazolo[1,5-a]pyrimidinamine::2-methyl-3-phenyl-5-propan-2-yl-N-(pyridin-2-ylmethyl)pyrazolo[1,5-a]pyrimidin-7-amine::MLS000762881::SMR000439709::cid_1966501

SMILES: CC(C)c1cc(NCc2ccccn2)n2nc(C)c(-c3ccccc3)c2n1

InChI Key: InChIKey=RMGILKZSADYARH-UHFFFAOYSA-N

Data: 2 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 58076   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
streptokinase A precursor (Streptococcus pyogenes M1 GAS)	BDBM58076 ((5-Isopropyl-2-methyl-3-phenyl-pyrazolo[1,5-a]pyri...) Show SMILES CC(C)c1cc(NCc2ccccn2)n2nc(C)c(-c3ccccc3)c2n1 Show InChI InChI=1S/C22H23N5/c1-15(2)19-13-20(24-14-18-11-7-8-12-23-18)27-22(25-19)21(16(3)26-27)17-9-5-4-6-10-17/h4-13,15,24H,14H2,1-3H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	6.95E+3	n/a	n/a	n/a	n/a
Broad Institute Curated by PubChem BioAssay					Assay Description Keywords: Group A streptococcus, GAS, streptokinase, expression, virulence, inhibition, dose response, EC50 Assay Overview: The goal of this assa...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2736PBV
					More data for this Ligand-Target Pair
C-C chemokine receptor type 6 (CCR6) (Homo sapiens (Human))	BDBM58076 ((5-Isopropyl-2-methyl-3-phenyl-pyrazolo[1,5-a]pyri...) Show SMILES CC(C)c1cc(NCc2ccccn2)n2nc(C)c(-c3ccccc3)c2n1 Show InChI InChI=1S/C22H23N5/c1-15(2)19-13-20(24-14-18-11-7-8-12-23-18)27-22(25-19)21(16(3)26-27)17-9-5-4-6-10-17/h4-13,15,24H,14H2,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	>6.66E+4	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute(SBMRI, San Diego, CA...				PubChem Bioassay (2011) BindingDB Entry DOI: 10.7270/Q20P0XHD
					More data for this Ligand-Target Pair
Beta-galactosidase (Escherichia coli)	BDBM58076 ((5-Isopropyl-2-methyl-3-phenyl-pyrazolo[1,5-a]pyri...) Show SMILES CC(C)c1cc(NCc2ccccn2)n2nc(C)c(-c3ccccc3)c2n1 Show InChI InChI=1S/C22H23N5/c1-15(2)19-13-20(24-14-18-11-7-8-12-23-18)27-22(25-19)21(16(3)26-27)17-9-5-4-6-10-17/h4-13,15,24H,14H2,1-3H3	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	>6.66E+4	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute(SBMRI, San Diego, C...				PubChem Bioassay (2011) BindingDB Entry DOI: 10.7270/Q2NG4P4X
					More data for this Ligand-Target Pair