BDBM58113 2-(1H-Benzoimidazol-2-yl)-4-benzyl-5-methyl-2,4-dihydro-pyrazol-3-one::2-(1H-benzimidazol-2-yl)-4-benzyl-5-methyl-2-pyrazolin-3-one::2-(1H-benzimidazol-2-yl)-4-benzyl-5-methyl-4H-pyrazol-3-one::2-(1H-benzimidazol-2-yl)-5-methyl-4-(phenylmethyl)-4H-pyrazol-3-one::CHEMBL3114983::MLS000762809::SMR000439826::cid_3915969

SMILES: Cc1[nH]n(-c2nc3ccccc3[nH]2)c(=O)c1Cc1ccccc1

InChI Key: InChIKey=CETPVAKYBIKMHV-UHFFFAOYSA-N

Data: 1 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 58113   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3 (Homo sapiens (Human))	BDBM58113 (2-(1H-Benzoimidazol-2-yl)-4-benzyl-5-methyl-2,4-di...) Show SMILES Cc1[nH]n(-c2nc3ccccc3[nH]2)c(=O)c1Cc1ccccc1 Show InChI InChI=1S/C18H16N4O/c1-12-14(11-13-7-3-2-4-8-13)17(23)22(21-12)18-19-15-9-5-6-10-16(15)20-18/h2-10,21H,11H2,1H3,(H,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	480	n/a	n/a	n/a	n/a	n/a	n/a
Hyogo University of Health Science Curated by ChEMBL					Assay Description Inhibition of demethylase activity of PCA-1 (unknown origin) using 3-methyl cytosine oligo DNA as substrate after 1 hr by RT-PCR analysis				Bioorg Med Chem Lett 24: 1071-4 (2014) Article DOI: 10.1016/j.bmcl.2014.01.008 BindingDB Entry DOI: 10.7270/Q2FF3TVD
					More data for this Ligand-Target Pair
Streptokinase A (Streptococcus pyogenes M1 GAS)	BDBM58113 (2-(1H-Benzoimidazol-2-yl)-4-benzyl-5-methyl-2,4-di...) Show SMILES Cc1[nH]n(-c2nc3ccccc3[nH]2)c(=O)c1Cc1ccccc1 Show InChI InChI=1S/C18H16N4O/c1-12-14(11-13-7-3-2-4-8-13)17(23)22(21-12)18-19-15-9-5-6-10-16(15)20-18/h2-10,21H,11H2,1H3,(H,19,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	1.50E+5	n/a	n/a	n/a	n/a
Broad Institute Curated by PubChem BioAssay					Assay Description Keywords: Group A streptococcus, GAS, streptokinase, expression, virulence, inhibition, dose response, EC50 Assay Overview: The goal of this assa...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2736PBV
					More data for this Ligand-Target Pair