BDBM58366 CHEMBL544584::MLS001165148::N-(phenylmethyl)-2-(2-pyridinyl)-4-quinazolinamine::N-(phenylmethyl)-2-pyridin-2-yl-quinazolin-4-amine::N-benzyl-2-pyridin-2-ylquinazolin-4-amine::SMR000540433::benzyl-[2-(2-pyridyl)quinazolin-4-yl]amine::cid_936435

SMILES: C(Nc1nc(nc2ccccc12)-c1ccccn1)c1ccccc1

InChI Key: InChIKey=LVDCGGJQSCVQAI-UHFFFAOYSA-N

Data: 1 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 58366   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM58366 (CHEMBL544584 | MLS001165148 | N-(phenylmethyl)-2-(...) Show SMILES C(Nc1nc(nc2ccccc12)-c1ccccn1)c1ccccc1 Show InChI InChI=1S/C20H16N4/c1-2-8-15(9-3-1)14-22-19-16-10-4-5-11-17(16)23-20(24-19)18-12-6-7-13-21-18/h1-13H,14H2,(H,22,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	2.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Biofor Inc. Curated by ChEMBL					Assay Description Inhibitory activity against phosphodiesterase 5 from human platelets				J Med Chem 38: 3547-57 (1995) BindingDB Entry DOI: 10.7270/Q2F190CB
					More data for this Ligand-Target Pair
streptokinase A precursor (Streptococcus pyogenes M1 GAS)	BDBM58366 (CHEMBL544584 | MLS001165148 | N-(phenylmethyl)-2-(...) Show SMILES C(Nc1nc(nc2ccccc12)-c1ccccn1)c1ccccc1 Show InChI InChI=1S/C20H16N4/c1-2-8-15(9-3-1)14-22-19-16-10-4-5-11-17(16)23-20(24-19)18-12-6-7-13-21-18/h1-13H,14H2,(H,22,23,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PCBioAssay	n/a	n/a	n/a	n/a	1.50E+5	n/a	n/a	n/a	n/a
Broad Institute Curated by PubChem BioAssay					Assay Description Keywords: Group A streptococcus, GAS, streptokinase, expression, virulence, inhibition, dose response, EC50 Assay Overview: The goal of this assa...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2736PBV
					More data for this Ligand-Target Pair