BDBM59116 Hymenialdisine, 27k
SMILES: CC(=O)NC1=NC(=O)C(N1)=C1CCNC(=O)c2[nH]c3ccc(Br)cc3c12
InChI Key: InChIKey=ZVRBGLIBMQOREJ-UHFFFAOYSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cyclin-dependent kinase 1 (Homo sapiens (Human)) | BDBM59116 (Hymenialdisine, 27k) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >10 | n/a | n/a | n/a | n/a | 7.2 | n/a |
Genomics Institute of the Novartis Research Foundation | Assay Description In vitro kinase assay using SPA assay kit from Amersham Pharmacia Biotech, Uk. | Chem Biol 11: 247-59 (2004) Article DOI: 10.1016/j.chembiol.2004.01.015 BindingDB Entry DOI: 10.7270/Q2FN14M9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 5 regulatory subunit 1 (Homo sapiens (Human)) | BDBM59116 (Hymenialdisine, 27k) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5.11E+3 | n/a | n/a | n/a | n/a | 7.2 | n/a |
Genomics Institute of the Novartis Research Foundation | Assay Description In vitro kinase assay using SPA assay kit from Amersham Pharmacia Biotech, Uk. | Chem Biol 11: 247-59 (2004) Article DOI: 10.1016/j.chembiol.2004.01.015 BindingDB Entry DOI: 10.7270/Q2FN14M9 | |||||||||||
More data for this Ligand-Target Pair |