BDBM59151 5247489

SMILES: CC(C=Cc1ccco1)=NCCCCNC(=O)C=Cc1ccco1

InChI Key: InChIKey=XLVYNTRXJJIIGS-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 59151   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation Factor VIII (Homo sapiens (Human))	BDBM59151 (5247489) Show SMILES CC(C=Cc1ccco1)=NCCCCNC(=O)C=Cc1ccco1 |w:18.19,9.10,2.1| Show InChI InChI=1S/C19H22N2O3/c1-16(8-9-17-6-4-14-23-17)20-12-2-3-13-21-19(22)11-10-18-7-5-15-24-18/h4-11,14-15H,2-3,12-13H2,1H3,(H,21,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.61E+4	n/a	n/a	n/a	n/a	n/a	37
University of Washington					Assay Description Inhibition of factor VIII C2 domain.				Chem Biol 11: 1413-22 (2004) Article DOI: 10.1016/j.chembiol.2004.08.006 BindingDB Entry DOI: 10.7270/Q29W0CX1
					More data for this Ligand-Target Pair