BDBM59152 5523453

SMILES: CCOC(=O)c1c(NC(=S)NC(=O)c2ccccc2)sc2CC(C)CCc12

InChI Key: InChIKey=SFWXGIKEVFVLKV-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 59152   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation Factor VIII (Homo sapiens (Human))	BDBM59152 (5523453) Show SMILES CCOC(=O)c1c(NC(=S)NC(=O)c2ccccc2)sc2CC(C)CCc12 Show InChI InChI=1S/C20H22N2O3S2/c1-3-25-19(24)16-14-10-9-12(2)11-15(14)27-18(16)22-20(26)21-17(23)13-7-5-4-6-8-13/h4-8,12H,3,9-11H2,1-2H3,(H2,21,22,23,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.77E+4	n/a	n/a	n/a	n/a	n/a	37
University of Washington					Assay Description Inhibition of factor VIII C2 domain.				Chem Biol 11: 1413-22 (2004) Article DOI: 10.1016/j.chembiol.2004.08.006 BindingDB Entry DOI: 10.7270/Q29W0CX1
					More data for this Ligand-Target Pair