BDBM59194 4-aminothiazole, 2.0
SMILES: Nc1nc(Nc2ccc(Cl)cc2)sc1C(=O)c1cccc(c1)N(=O)=O
InChI Key: InChIKey=YQRVBHMYUSGXHL-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cyclin-dependent-like kinase 5 (Homo sapiens (Human)) | BDBM59194 (4-aminothiazole, 2.0) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | 660 | n/a | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Harvard Medical School | Assay Description Cdk5, 33P-ATP and cofactors were added in the presence of tau protein. The reaction mixture was incubated to allow Cdk5 to transfer 33P from ATP to ... | Chem Biol 12: 811-23 (2005) Article DOI: 10.1016/j.chembiol.2005.05.011 BindingDB Entry DOI: 10.7270/Q2ST7N84 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent-like kinase 5 (Homo sapiens (Human)) | BDBM59194 (4-aminothiazole, 2.0) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | 690 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Harvard Medical School | Assay Description Cdk5, 33P-ATP and cofactors were added in the presence of tau protein. The reaction mixture was incubated to allow Cdk5 to transfer 33P from ATP to ... | Chem Biol 12: 811-23 (2005) Article DOI: 10.1016/j.chembiol.2005.05.011 BindingDB Entry DOI: 10.7270/Q2ST7N84 | |||||||||||
More data for this Ligand-Target Pair |