BDBM59216 Pepstatin analog, 4
SMILES: CC(C)C[C@@H](NC(=O)[C@H](NC(=O)CCCCCCCCCCCCCCC(=O)N[C@H](CC(N)=O)C(=O)N[C@@H](Cc1ccccc1)C(O)=O)C(C)O)C(=O)NCCc1cccc(O)c1
InChI Key: InChIKey=FDMXXQQBWCZJMY-KUMZHBIPSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Human herpesvirus 1 protease (Human herpesvirus 1 (strain 17) (HHV-1) (Human her...) | BDBM59216 (Pepstatin analog, 4) | MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 1.13E+3 | n/a | 4.40E+3 | n/a | n/a | n/a | n/a | 5.52 | n/a |
Purdue University | Assay Description The competitive assay requires two inhibitors to act by a purely competitive mechanism, whereas the binding site of on the inhibitors has been establ... | Chem Biol 12: 439-44 (2005) Article DOI: 10.1016/j.chembiol.2005.02.004 BindingDB Entry DOI: 10.7270/Q2JD4V68 | |||||||||||
More data for this Ligand-Target Pair |