BindingDB PrimarySearch

BDBM59704 1-(3,4-dichlorophenyl)-3-[4-[(3,4-dimethyl-1,2-oxazol-5-yl)sulfamoyl]phenyl]urea::1-(3,4-dichlorophenyl)-3-[4-[(3,4-dimethyl-5-isoxazolyl)sulfamoyl]phenyl]urea::1-(3,4-dichlorophenyl)-3-[4-[(3,4-dimethylisoxazol-5-yl)sulfamoyl]phenyl]urea::4-({[(3,4-dichlorophenyl)amino]carbonyl}amino)-N-(3,4-dimethyl-5-isoxazolyl)benzenesulfonamide::MLS000050956::SMR000078689::cid_1188014

SMILES: Cc1noc(NS(=O)(=O)c2ccc(NC(=O)Nc3ccc(Cl)c(Cl)c3)cc2)c1C

InChI Key: InChIKey=MFDXKWQZOYSRTF-UHFFFAOYSA-N

Data: 1 KI 3 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 59704
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Purinergic receptor P2Y1 (Homo sapiens (Human))	BDBM59704 (1-(3,4-dichlorophenyl)-3-[4-[(3,4-dimethyl-1,2-oxa...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	1.30E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institutes of Health Curated by ChEMBL					Assay Description Displacement of [125I]MRS2500 from human P2Y1R expressed in Sf9 cell membrane				Bioorg Med Chem 20: 5254-61 (2012) Article DOI: 10.1016/j.bmc.2012.06.044 BindingDB Entry DOI: 10.7270/Q2BP03V2
National Institutes of Health Curated by ChEMBL					More data for this Ligand-Target Pair
Purinergic receptor P2Y1 (Homo sapiens (Human))	BDBM59704 (1-(3,4-dichlorophenyl)-3-[4-[(3,4-dimethyl-1,2-oxa...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
National Institutes of Health Curated by ChEMBL					Assay Description Antagonist activity at human P2Y1R expressed in human 1321N1 cells assessed as inhibition of 2-MeSADP-induced increase in intracellular inositol phos...				Bioorg Med Chem 20: 5254-61 (2012) Article DOI: 10.1016/j.bmc.2012.06.044 BindingDB Entry DOI: 10.7270/Q2BP03V2
National Institutes of Health Curated by ChEMBL					More data for this Ligand-Target Pair
leucine aminopeptidase (Plasmodium falciparum 3D7)	BDBM59704 (1-(3,4-dichlorophenyl)-3-[4-[(3,4-dimethyl-1,2-oxa...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	9.03E+3	n/a	n/a	n/a	n/a	n/a	n/a
SRMLSC Curated by PubChem BioAssay					Assay Description Southern Research Molecular Libraries Screening Center (SRMLSC) Southern Research Institute (Birmingham, Alabama) NIH Molecular Libraries Screening...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q27W69N8
SRMLSC Curated by PubChem BioAssay					More data for this Ligand-Target Pair
TPA: Essential protein of the mitochondrial intermembrane space (Saccharomyces cerevisiae S288c)	BDBM59704 (1-(3,4-dichlorophenyl)-3-[4-[(3,4-dimethyl-1,2-oxa...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	4.31E+4	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute(SBMRI, San Diego, CA...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2F18X6W
					More data for this Ligand-Target Pair