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BDBM60397 MLS000115777::N-(4-hydroxyphenyl)-8-quinolinesulfonamide::N-(4-hydroxyphenyl)quinoline-8-sulfonamide::SMR000092793::cid_894115

SMILES: Oc1ccc(NS(=O)(=O)c2cccc3cccnc23)cc1

InChI Key: InChIKey=KVFNSUPFXGYOKN-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 60397   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cytochrome b-c1 complex subunit 7


(Homo sapiens)
BDBM60397
PNG
(MLS000115777 | N-(4-hydroxyphenyl)-8-quinolinesulf...)
Show SMILES Oc1ccc(NS(=O)(=O)c2cccc3cccnc23)cc1
Show InChI InChI=1S/C15H12N2O3S/c18-13-8-6-12(7-9-13)17-21(19,20)14-5-1-3-11-4-2-10-16-15(11)14/h1-10,17-18H
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>2.00E+4n/an/an/an/an/an/a



Yonsei University

Curated by ChEMBL


Assay Description
Modulation of UQCRB in human HepG2 cells assessed as inhibition of HIF-1alpha for 4 hrs under 1%O2 by Western blot analysis


J Med Chem 57: 7990-8 (2014)

More data for this
Ligand-Target Pair
large T antigen


(Simian virus 40)
BDBM60397
PNG
(MLS000115777 | N-(4-hydroxyphenyl)-8-quinolinesulf...)
Show SMILES Oc1ccc(NS(=O)(=O)c2cccc3cccnc23)cc1
Show InChI InChI=1S/C15H12N2O3S/c18-13-8-6-12(7-9-13)17-21(19,20)14-5-1-3-11-4-2-10-16-15(11)14/h1-10,17-18H
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem

Similars

PCBioAssay
n/an/a 7.36E+3n/an/an/an/an/an/a



Southern Research Specialized Biocontainment Screening Center

Curated by PubChem BioAssay


Assay Description
A biochemical assay using the ADP-Hunter methodology, purified TAg, and ATP to identify compounds that inhibit the ATPase activity of Tag Southern Re...


Citation and Details
More data for this
Ligand-Target Pair