BDBM60509 US9085531, 125
SMILES: CN1Cc2ccccc2C(C1Cl)c1ccc2[nH]ncc2c1
InChI Key:
Data: 3 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sodium-dependent noradrenaline transporter (Homo sapiens (Human)) | BDBM60509 (US9085531, 125) | Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 2.60 | n/a | n/a | n/a | n/a | n/a | n/a | 7.4 | n/a |
Albany Molecular Research, Inc.; Bristol-Myers Squibb Company US Patent | Assay Description In order to evaluate the relative affinity of the various compounds at the NE, DA and 5HT transporters, HEK293E cell lines were developed to express ... | US Patent US9085531 (2015) BindingDB Entry DOI: 10.7270/Q24X56JQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent dopamine transporter (Homo sapiens (Human)) | BDBM60509 (US9085531, 125) | NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 11.5 | n/a | n/a | n/a | n/a | n/a | n/a | 7.4 | n/a |
Albany Molecular Research, Inc.; Bristol-Myers Squibb Company US Patent | Assay Description In order to evaluate the relative affinity of the various compounds at the NE, DA and 5HT transporters, HEK293E cell lines were developed to express ... | US Patent US9085531 (2015) BindingDB Entry DOI: 10.7270/Q24X56JQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Homo sapiens (Human)) | BDBM60509 (US9085531, 125) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 21.3 | n/a | n/a | n/a | n/a | n/a | n/a | 7.4 | n/a |
Albany Molecular Research, Inc.; Bristol-Myers Squibb Company US Patent | Assay Description In order to evaluate the relative affinity of the various compounds at the NE, DA and 5HT transporters, HEK293E cell lines were developed to express ... | US Patent US9085531 (2015) BindingDB Entry DOI: 10.7270/Q24X56JQ | |||||||||||
More data for this Ligand-Target Pair |