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BDBM60970 Ethoxzolamide (EZA)

SMILES: CCOc1ccc2N=CC(CS(N)(=O)=O)Sc2c1

InChI Key: InChIKey=BSIVPMYWAXTFRA-UHFFFAOYNA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 60970   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Carbonic anhydrase 2


(Homo sapiens (Human))
BDBM60970
PNG
(Ethoxzolamide (EZA))
Show SMILES CCOc1ccc2N=CC(CS(N)(=O)=O)Sc2c1 |c:7|
Show InChI InChI=1/C11H14N2O3S2/c1-2-16-8-3-4-10-11(5-8)17-9(6-13-10)7-18(12,14)15/h3-6,9H,2,7H2,1H3,(H2,12,14,15)
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MMDB

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PC sid
UniChem
Article
PubMed
11 -10.8n/an/an/an/an/a7.525



Kirklareli University



Assay Description
Phenol red (at a concentration of 0.2 mM) has been used as indicator, working at the absorbance maximum of 557 nm, with 10 mM Tris-HCl (pH 7.5) as bu...


J Enzyme Inhib Med Chem 28: 316-9 (2013)


Article DOI: 10.3109/14756366.2011.637200
BindingDB Entry DOI: 10.7270/Q208647F
More data for this
Ligand-Target Pair
Carbonic anhydrase 1


(Homo sapiens (Human))
BDBM60970
PNG
(Ethoxzolamide (EZA))
Show SMILES CCOc1ccc2N=CC(CS(N)(=O)=O)Sc2c1 |c:7|
Show InChI InChI=1/C11H14N2O3S2/c1-2-16-8-3-4-10-11(5-8)17-9(6-13-10)7-18(12,14)15/h3-6,9H,2,7H2,1H3,(H2,12,14,15)
PDB
MMDB

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KEGG

UniProtKB/SwissProt

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DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
30 -10.3n/an/an/an/an/a7.525



Kirklareli University



Assay Description
Phenol red (at a concentration of 0.2 mM) has been used as indicator, working at the absorbance maximum of 557 nm, with 10 mM Tris-HCl (pH 7.5) as bu...


J Enzyme Inhib Med Chem 28: 316-9 (2013)


Article DOI: 10.3109/14756366.2011.637200
BindingDB Entry DOI: 10.7270/Q208647F
More data for this
Ligand-Target Pair
Carbonic anhydrase 6 (CA-VI)


(Homo sapiens (Human))
BDBM60970
PNG
(Ethoxzolamide (EZA))
Show SMILES CCOc1ccc2N=CC(CS(N)(=O)=O)Sc2c1 |c:7|
Show InChI InChI=1/C11H14N2O3S2/c1-2-16-8-3-4-10-11(5-8)17-9(6-13-10)7-18(12,14)15/h3-6,9H,2,7H2,1H3,(H2,12,14,15)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
50 -9.95n/an/an/an/an/a7.525



Kirklareli University



Assay Description
Phenol red (at a concentration of 0.2 mM) has been used as indicator, working at the absorbance maximum of 557 nm, with 10 mM Tris-HCl (pH 7.5) as bu...


J Enzyme Inhib Med Chem 28: 316-9 (2013)


Article DOI: 10.3109/14756366.2011.637200
BindingDB Entry DOI: 10.7270/Q208647F
More data for this
Ligand-Target Pair