BDBM60970 Ethoxzolamide (EZA)

SMILES: CCOc1ccc2N=CC(CS(N)(=O)=O)Sc2c1

InChI Key: InChIKey=BSIVPMYWAXTFRA-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 60970   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM60970 (Ethoxzolamide (EZA)) Show SMILES CCOc1ccc2N=CC(CS(N)(=O)=O)Sc2c1 |c:7| Show InChI InChI=1S/C11H14N2O3S2/c1-2-16-8-3-4-10-11(5-8)17-9(6-13-10)7-18(12,14)15/h3-6,9H,2,7H2,1H3,(H2,12,14,15)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	11	-10.8	n/a	n/a	n/a	n/a	n/a	7.5	25
Kirklareli University					Assay Description Phenol red (at a concentration of 0.2 mM) has been used as indicator, working at the absorbance maximum of 557 nm, with 10 mM Tris-HCl (pH 7.5) as bu...				J Enzyme Inhib Med Chem 28: 316-9 (2013) Article DOI: 10.3109/14756366.2011.637200 BindingDB Entry DOI: 10.7270/Q208647F
					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Homo sapiens (Human))	BDBM60970 (Ethoxzolamide (EZA)) Show SMILES CCOc1ccc2N=CC(CS(N)(=O)=O)Sc2c1 |c:7| Show InChI InChI=1S/C11H14N2O3S2/c1-2-16-8-3-4-10-11(5-8)17-9(6-13-10)7-18(12,14)15/h3-6,9H,2,7H2,1H3,(H2,12,14,15)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	30	-10.3	n/a	n/a	n/a	n/a	n/a	7.5	25
Kirklareli University					Assay Description Phenol red (at a concentration of 0.2 mM) has been used as indicator, working at the absorbance maximum of 557 nm, with 10 mM Tris-HCl (pH 7.5) as bu...				J Enzyme Inhib Med Chem 28: 316-9 (2013) Article DOI: 10.3109/14756366.2011.637200 BindingDB Entry DOI: 10.7270/Q208647F
					More data for this Ligand-Target Pair
Carbonic anhydrase 6 (CA-VI) (Homo sapiens (Human))	BDBM60970 (Ethoxzolamide (EZA)) Show SMILES CCOc1ccc2N=CC(CS(N)(=O)=O)Sc2c1 |c:7| Show InChI InChI=1S/C11H14N2O3S2/c1-2-16-8-3-4-10-11(5-8)17-9(6-13-10)7-18(12,14)15/h3-6,9H,2,7H2,1H3,(H2,12,14,15)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	50	-9.95	n/a	n/a	n/a	n/a	n/a	7.5	25
Kirklareli University					Assay Description Phenol red (at a concentration of 0.2 mM) has been used as indicator, working at the absorbance maximum of 557 nm, with 10 mM Tris-HCl (pH 7.5) as bu...				J Enzyme Inhib Med Chem 28: 316-9 (2013) Article DOI: 10.3109/14756366.2011.637200 BindingDB Entry DOI: 10.7270/Q208647F
					More data for this Ligand-Target Pair