BDBM61910 6-fluoranyl-2-phenyl-1,2-benzothiazol-3-one::6-fluoro-2-phenyl-1,2-benzothiazol-3-one::KUC103671N::cid_1510378

SMILES: Fc1ccc2c(c1)sn(-c1ccccc1)c2=O

InChI Key: InChIKey=DSSXORGEYXPNQS-UHFFFAOYSA-N

Data: 6 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 61910   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
hexokinase (Trypanosoma brucei)	BDBM61910 (6-fluoranyl-2-phenyl-1,2-benzothiazol-3-one | 6-fl...) Show SMILES Fc1ccc2c(c1)sn(-c1ccccc1)c2=O Show InChI InChI=1S/C13H8FNOS/c14-9-6-7-11-12(8-9)17-15(13(11)16)10-4-2-1-3-5-10/h1-8H	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	2.31E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Pittsburgh Molecular Library Screening Center Curated by PubChem BioAssay					Assay Description Excerpt from MH0882340 application (Dr. James Morris, Clemson University) Trypanosoma brucei, the digenic protozoan parasite that causes African slee...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q21834XK
					More data for this Ligand-Target Pair
MSRA protein (Bos taurus)	BDBM61910 (6-fluoranyl-2-phenyl-1,2-benzothiazol-3-one | 6-fl...) Show SMILES Fc1ccc2c(c1)sn(-c1ccccc1)c2=O Show InChI InChI=1S/C13H8FNOS/c14-9-6-7-11-12(8-9)17-15(13(11)16)10-4-2-1-3-5-10/h1-8H	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	>1.04E+5	n/a	n/a	n/a	n/a
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay					Assay Description Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...				PubChem Bioassay (2012) BindingDB Entry DOI: 10.7270/Q2BZ64NT
					More data for this Ligand-Target Pair
Beta lactamase (Pseudomonas aeruginosa)	BDBM61910 (6-fluoranyl-2-phenyl-1,2-benzothiazol-3-one | 6-fl...) Show SMILES Fc1ccc2c(c1)sn(-c1ccccc1)c2=O Show InChI InChI=1S/C13H8FNOS/c14-9-6-7-11-12(8-9)17-15(13(11)16)10-4-2-1-3-5-10/h1-8H	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	2.34E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay									PubChem Bioassay (2012) BindingDB Entry DOI: 10.7270/Q2XS5T0R
					More data for this Ligand-Target Pair
Mannose-6-phosphate isomerase (Homo sapiens (Human))	BDBM61910 (6-fluoranyl-2-phenyl-1,2-benzothiazol-3-one | 6-fl...) Show SMILES Fc1ccc2c(c1)sn(-c1ccccc1)c2=O Show InChI InChI=1S/C13H8FNOS/c14-9-6-7-11-12(8-9)17-15(13(11)16)10-4-2-1-3-5-10/h1-8H	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Sanford-Burnham Medical Research Institute Curated by ChEMBL					Assay Description Inhibition of phosphomannose isomerase (unknown origin)				Bioorg Med Chem Lett 24: 4308-11 (2014) Article DOI: 10.1016/j.bmcl.2014.07.013 BindingDB Entry DOI: 10.7270/Q2GX4D7W
					More data for this Ligand-Target Pair
phosphatase, orphan 1 (Homo sapiens (Human))	BDBM61910 (6-fluoranyl-2-phenyl-1,2-benzothiazol-3-one | 6-fl...) Show SMILES Fc1ccc2c(c1)sn(-c1ccccc1)c2=O Show InChI InChI=1S/C13H8FNOS/c14-9-6-7-11-12(8-9)17-15(13(11)16)10-4-2-1-3-5-10/h1-8H	KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	790	n/a	n/a	n/a	n/a	n/a	n/a
Sanford-Burnham Medical Research Institute Curated by ChEMBL					Assay Description Inhibition of PHOSPHO1 phosphoethanolamine activity (unknown origin) assessed as amount of inorganic phosphate release after 30 mins				Bioorg Med Chem Lett 24: 4308-11 (2014) Article DOI: 10.1016/j.bmcl.2014.07.013 BindingDB Entry DOI: 10.7270/Q2GX4D7W
					More data for this Ligand-Target Pair
phosphomannomutase 2 (Homo sapiens (Human))	BDBM61910 (6-fluoranyl-2-phenyl-1,2-benzothiazol-3-one | 6-fl...) Show SMILES Fc1ccc2c(c1)sn(-c1ccccc1)c2=O Show InChI InChI=1S/C13H8FNOS/c14-9-6-7-11-12(8-9)17-15(13(11)16)10-4-2-1-3-5-10/h1-8H	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Sanford-Burnham Medical Research Institute Curated by ChEMBL					Assay Description Inhibition of PMM2 (unknown origin)				Bioorg Med Chem Lett 24: 4308-11 (2014) Article DOI: 10.1016/j.bmcl.2014.07.013 BindingDB Entry DOI: 10.7270/Q2GX4D7W
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase RIPK2 (Homo sapiens (Human))	BDBM61910 (6-fluoranyl-2-phenyl-1,2-benzothiazol-3-one | 6-fl...) Show SMILES Fc1ccc2c(c1)sn(-c1ccccc1)c2=O Show InChI InChI=1S/C13H8FNOS/c14-9-6-7-11-12(8-9)17-15(13(11)16)10-4-2-1-3-5-10/h1-8H	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	5.43E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay									PubChem Bioassay (2012) BindingDB Entry DOI: 10.7270/Q2T15278
					More data for this Ligand-Target Pair