BDBM62221 2-(4,6-dimethylisoxazolo[5,4-b]pyridin-3-yl)oxy-1-[3-methyl-4-(m-tolyl)piperazino]ethanone::2-[(4,6-dimethyl-3-isoxazolo[5,4-b]pyridinyl)oxy]-1-[3-methyl-4-(3-methylphenyl)-1-piperazinyl]ethanone::2-[(4,6-dimethyl-[1,2]oxazolo[5,4-b]pyridin-3-yl)oxy]-1-[3-methyl-4-(3-methylphenyl)piperazin-1-yl]ethanone::KUC103676N::cid_44473132

SMILES: CC1CN(CCN1c1cccc(C)c1)C(=O)COc1noc2nc(C)cc(C)c12

InChI Key: InChIKey=BKCAQRNMUSHHJI-UHFFFAOYSA-N

Data: 4 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 62221   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
regulator of G-protein signaling 4 (Homo sapiens (Human))	BDBM62221 (2-(4,6-dimethylisoxazolo[5,4-b]pyridin-3-yl)oxy-1-...) Show SMILES CC1CN(CCN1c1cccc(C)c1)C(=O)COc1noc2nc(C)cc(C)c12 Show InChI InChI=1S/C22H26N4O3/c1-14-6-5-7-18(10-14)26-9-8-25(12-17(26)4)19(27)13-28-22-20-15(2)11-16(3)23-21(20)29-24-22/h5-7,10-11,17H,8-9,12-13H2,1-4H3	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	PCBioAssay	n/a	n/a	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a
NMMLSC Curated by PubChem BioAssay					Assay Description University of New Mexico Assay Overview: Assay Support: NIH R21NS057014 HTS to identify small molecule regulators of RGS family protein interaction...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2CF9NJZ
					More data for this Ligand-Target Pair
Regulator of G-protein signaling 8 (Homo sapiens (Human))	BDBM62221 (2-(4,6-dimethylisoxazolo[5,4-b]pyridin-3-yl)oxy-1-...) Show SMILES CC1CN(CCN1c1cccc(C)c1)C(=O)COc1noc2nc(C)cc(C)c12 Show InChI InChI=1S/C22H26N4O3/c1-14-6-5-7-18(10-14)26-9-8-25(12-17(26)4)19(27)13-28-22-20-15(2)11-16(3)23-21(20)29-24-22/h5-7,10-11,17H,8-9,12-13H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	PCBioAssay	n/a	n/a	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a
NMMLSC Curated by PubChem BioAssay					Assay Description University of New Mexico Assay Overview: Assay Support: NIH R21NS057014 HTS to identify small molecule regulators of RGS family protein interaction...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2M043TQ
					More data for this Ligand-Target Pair
regulator of G-protein signalling 16 (Homo sapiens (Human))	BDBM62221 (2-(4,6-dimethylisoxazolo[5,4-b]pyridin-3-yl)oxy-1-...) Show SMILES CC1CN(CCN1c1cccc(C)c1)C(=O)COc1noc2nc(C)cc(C)c12 Show InChI InChI=1S/C22H26N4O3/c1-14-6-5-7-18(10-14)26-9-8-25(12-17(26)4)19(27)13-28-22-20-15(2)11-16(3)23-21(20)29-24-22/h5-7,10-11,17H,8-9,12-13H2,1-4H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	PCBioAssay	n/a	n/a	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a
NMMLSC Curated by PubChem BioAssay					Assay Description University of New Mexico Assay Overview: Assay Support: NIH R21NS057014 HTS to identify small molecule regulators of RGS family protein interaction...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2VH5M8G
					More data for this Ligand-Target Pair
RGS7 (Homo sapiens (Human))	BDBM62221 (2-(4,6-dimethylisoxazolo[5,4-b]pyridin-3-yl)oxy-1-...) Show SMILES CC1CN(CCN1c1cccc(C)c1)C(=O)COc1noc2nc(C)cc(C)c12 Show InChI InChI=1S/C22H26N4O3/c1-14-6-5-7-18(10-14)26-9-8-25(12-17(26)4)19(27)13-28-22-20-15(2)11-16(3)23-21(20)29-24-22/h5-7,10-11,17H,8-9,12-13H2,1-4H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	PCBioAssay	n/a	n/a	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a
NMMLSC Curated by PubChem BioAssay					Assay Description University of New Mexico Assay Overview: Assay Support: NIH R21NS057014 HTS to identify small molecule regulators of RGS family protein interaction...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2416VG3
					More data for this Ligand-Target Pair