BDBM62926 2-(2-pyridinyl)-3H-benzimidazol-5-amine::2-Pyridin-2-yl-1H-benzoimidazol-5-ylamine::2-pyridin-2-yl-3H-benzimidazol-5-amine::CHEMBL199925::MLS000528495::SMR000121070::[2-(2-pyridyl)-3H-benzimidazol-5-yl]amine::cid_542828

SMILES: Nc1ccc2nc([nH]c2c1)-c1ccccn1

InChI Key: InChIKey=ITFXYBZUPPBWEC-UHFFFAOYSA-N

Data: 3 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 62926   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hsf1 protein (Mus musculus)	BDBM62926 (2-(2-pyridinyl)-3H-benzimidazol-5-amine | 2-Pyridi...) Show SMILES Nc1ccc2nc([nH]c2c1)-c1ccccn1 Show InChI InChI=1S/C12H10N4/c13-8-4-5-9-11(7-8)16-12(15-9)10-3-1-2-6-14-10/h1-7H,13H2,(H,15,16)	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	2.32E+4	n/a	n/a	n/a	n/a
Broad Institute Curated by PubChem BioAssay					Assay Description Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2MW2FKX
					More data for this Ligand-Target Pair
Methionine aminopeptidase 2 (Homo sapiens (Human))	BDBM62926 (2-(2-pyridinyl)-3H-benzimidazol-5-amine | 2-Pyridi...) Show SMILES Nc1ccc2nc([nH]c2c1)-c1ccccn1 Show InChI InChI=1S/C12H10N4/c13-8-4-5-9-11(7-8)16-12(15-9)10-3-1-2-6-14-10/h1-7H,13H2,(H,15,16)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£t Heidelberg Curated by ChEMBL					Assay Description Inhibition of human MetAP2 expressed in baculovirus infected Sf9 cells				Bioorg Med Chem Lett 20: 4038-44 (2010) Article DOI: 10.1016/j.bmcl.2010.05.093 BindingDB Entry DOI: 10.7270/Q2RF5W0K
					More data for this Ligand-Target Pair
Methionine Aminopeptidase (MAP) (Escherichia coli (strain K12))	BDBM62926 (2-(2-pyridinyl)-3H-benzimidazol-5-amine | 2-Pyridi...) Show SMILES Nc1ccc2nc([nH]c2c1)-c1ccccn1 Show InChI InChI=1S/C12H10N4/c13-8-4-5-9-11(7-8)16-12(15-9)10-3-1-2-6-14-10/h1-7H,13H2,(H,15,16)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	967	n/a	n/a	n/a	n/a	n/a	n/a
Saarland University Curated by ChEMBL					Assay Description Inhibition of Co2+ loaded MetAP expressed in Escherichia coli				J Med Chem 49: 511-22 (2006) Article DOI: 10.1021/jm050476z BindingDB Entry DOI: 10.7270/Q2N58KXD
					More data for this Ligand-Target Pair
protein artemis isoform a (Homo sapiens (Human))	BDBM62926 (2-(2-pyridinyl)-3H-benzimidazol-5-amine | 2-Pyridi...) Show SMILES Nc1ccc2nc([nH]c2c1)-c1ccccn1 Show InChI InChI=1S/C12H10N4/c13-8-4-5-9-11(7-8)16-12(15-9)10-3-1-2-6-14-10/h1-7H,13H2,(H,15,16)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	1.67E+4	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego CA...				PubChem Bioassay (2013) BindingDB Entry DOI: 10.7270/Q2MC8XP5
					More data for this Ligand-Target Pair