BDBM63209 3-(1-phenyl-2-thioxo-2,3-dihydro-1H-imidazol-4-yl)-2H-chromen-2-one::3-(1-phenyl-2-thioxo-4-imidazolin-4-yl)coumarin::3-(3-phenyl-2-sulfanylidene-1H-imidazol-5-yl)-1-benzopyran-2-one::3-(3-phenyl-2-sulfanylidene-1H-imidazol-5-yl)chromen-2-one::CHEMBL1352521::MLS000583508::SMR000206694::cid_3380837

SMILES: O=c1oc2ccccc2cc1-c1cn(-c2ccccc2)c(=S)[nH]1

InChI Key: InChIKey=PQLXBUALUZFSAJ-UHFFFAOYSA-N

Data: 3 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 63209   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hsf1 protein (Mus musculus)	BDBM63209 (3-(1-phenyl-2-thioxo-2,3-dihydro-1H-imidazol-4-yl)...) Show SMILES O=c1oc2ccccc2cc1-c1cn(-c2ccccc2)c(=S)[nH]1 Show InChI InChI=1S/C18H12N2O2S/c21-17-14(10-12-6-4-5-9-16(12)22-17)15-11-20(18(23)19-15)13-7-2-1-3-8-13/h1-11H,(H,19,23)	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	<160	n/a	n/a	n/a	n/a
Broad Institute Curated by PubChem BioAssay					Assay Description Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2MW2FKX
					More data for this Ligand-Target Pair
Collagenase 3 (Homo sapiens (Human))	BDBM63209 (3-(1-phenyl-2-thioxo-2,3-dihydro-1H-imidazol-4-yl)...) Show SMILES O=c1oc2ccccc2cc1-c1cn(-c2ccccc2)c(=S)[nH]1 Show InChI InChI=1S/C18H12N2O2S/c21-17-14(10-12-6-4-5-9-16(12)22-17)15-11-20(18(23)19-15)13-7-2-1-3-8-13/h1-11H,(H,19,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.77E+5	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Napoli Federico II Via D. Montesano 49 Curated by ChEMBL					Assay Description Inhibition of human MMP13 using Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as substrate pre-incubated for 4 hrs before substrate addition measured ...				Eur J Med Chem 47: 143-52 (2012) Article DOI: 10.1016/j.ejmech.2011.10.035 BindingDB Entry DOI: 10.7270/Q280531P
					More data for this Ligand-Target Pair
BRCA1-associated RING domain protein 1 (Homo sapiens (Human))	BDBM63209 (3-(1-phenyl-2-thioxo-2,3-dihydro-1H-imidazol-4-yl)...) Show SMILES O=c1oc2ccccc2cc1-c1cn(-c2ccccc2)c(=S)[nH]1 Show InChI InChI=1S/C18H12N2O2S/c21-17-14(10-12-6-4-5-9-16(12)22-17)15-11-20(18(23)19-15)13-7-2-1-3-8-13/h1-11H,(H,19,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	3.53	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego CA...				PubChem Bioassay (2011) BindingDB Entry DOI: 10.7270/Q2DZ06SS
					More data for this Ligand-Target Pair
p53-Binding Protein HDMX (Homo sapiens (Human))	BDBM63209 (3-(1-phenyl-2-thioxo-2,3-dihydro-1H-imidazol-4-yl)...) Show SMILES O=c1oc2ccccc2cc1-c1cn(-c2ccccc2)c(=S)[nH]1 Show InChI InChI=1S/C18H12N2O2S/c21-17-14(10-12-6-4-5-9-16(12)22-17)15-11-20(18(23)19-15)13-7-2-1-3-8-13/h1-11H,(H,19,23)	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	3.74	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego CA...				PubChem Bioassay (2011) BindingDB Entry DOI: 10.7270/Q2PG1Q6D
					More data for this Ligand-Target Pair