BDBM6410 (3-Chlorophenyl)-{6-[5-(3-piperidin-1-yl-propylamino)-pyridin-3-yl]-pyrazin-2-yl}-amine::N-(3-chlorophenyl)-6-(5-{[3-(piperidin-1-yl)propyl]amino}pyridin-3-yl)pyrazin-2-amine::Pyrazine-Pyridine Biheteroaryl 53

SMILES: Clc1cccc(Nc2cncc(n2)-c2cncc(NCCCN3CCCCC3)c2)c1

InChI Key: InChIKey=SQOMHHDPYUXRBG-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 6410   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
VEGFR-2 (KDR) (Rattus norvegicus (rat))	BDBM6410 ((3-Chlorophenyl)-{6-[5-(3-piperidin-1-yl-propylami...) Show SMILES Clc1cccc(Nc2cncc(n2)-c2cncc(NCCCN3CCCCC3)c2)c1 Show InChI InChI=1S/C23H27ClN6/c24-19-6-4-7-20(13-19)28-23-17-26-16-22(29-23)18-12-21(15-25-14-18)27-8-5-11-30-9-2-1-3-10-30/h4,6-7,12-17,27H,1-3,5,8-11H2,(H,28,29)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	399	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical					Assay Description The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...				J Med Chem 48: 4892-909 (2005) Article DOI: 10.1021/jm058205b BindingDB Entry DOI: 10.7270/Q2NC5ZD5
					More data for this Ligand-Target Pair
Cyclin-Dependent Kinase 1 (CDK1) (Homo sapiens (Human))	BDBM6410 ((3-Chlorophenyl)-{6-[5-(3-piperidin-1-yl-propylami...) Show SMILES Clc1cccc(Nc2cncc(n2)-c2cncc(NCCCN3CCCCC3)c2)c1 Show InChI InChI=1S/C23H27ClN6/c24-19-6-4-7-20(13-19)28-23-17-26-16-22(29-23)18-12-21(15-25-14-18)27-8-5-11-30-9-2-1-3-10-30/h4,6-7,12-17,27H,1-3,5,8-11H2,(H,28,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5.39E+3	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical					Assay Description The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...				J Med Chem 48: 4892-909 (2005) Article DOI: 10.1021/jm058205b BindingDB Entry DOI: 10.7270/Q2NC5ZD5
					More data for this Ligand-Target Pair