BDBM6413 (3-Chloro-phenyl)-{6-[5-(3-phenyl-propylamino)-pyridin-3-yl]-pyrazin-2-yl}-amine::N-(3-chlorophenyl)-6-{5-[(3-phenylpropyl)amino]pyridin-3-yl}pyrazin-2-amine::Pyrazine-Pyridine Biheteroaryl 59

SMILES: Clc1cccc(Nc2cncc(n2)-c2cncc(NCCCc3ccccc3)c2)c1

InChI Key: InChIKey=NNTGNPPBTNKLPC-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 6413   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
VEGFR-2 (KDR) (Rattus norvegicus (rat))	BDBM6413 ((3-Chloro-phenyl)-{6-[5-(3-phenyl-propylamino)-pyr...) Show SMILES Clc1cccc(Nc2cncc(n2)-c2cncc(NCCCc3ccccc3)c2)c1 Show InChI InChI=1S/C24H22ClN5/c25-20-9-4-10-21(13-20)29-24-17-27-16-23(30-24)19-12-22(15-26-14-19)28-11-5-8-18-6-2-1-3-7-18/h1-4,6-7,9-10,12-17,28H,5,8,11H2,(H,29,30)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.28E+3	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical					Assay Description The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...				J Med Chem 48: 4892-909 (2005) Article DOI: 10.1021/jm058205b BindingDB Entry DOI: 10.7270/Q2NC5ZD5
					More data for this Ligand-Target Pair
Cyclin-Dependent Kinase 1 (CDK1) (Homo sapiens (Human))	BDBM6413 ((3-Chloro-phenyl)-{6-[5-(3-phenyl-propylamino)-pyr...) Show SMILES Clc1cccc(Nc2cncc(n2)-c2cncc(NCCCc3ccccc3)c2)c1 Show InChI InChI=1S/C24H22ClN5/c25-20-9-4-10-21(13-20)29-24-17-27-16-23(30-24)19-12-22(15-26-14-19)28-11-5-8-18-6-2-1-3-7-18/h1-4,6-7,9-10,12-17,28H,5,8,11H2,(H,29,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical					Assay Description The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...				J Med Chem 48: 4892-909 (2005) Article DOI: 10.1021/jm058205b BindingDB Entry DOI: 10.7270/Q2NC5ZD5
					More data for this Ligand-Target Pair