BDBM6437 (3-Chlorophenyl){6-[2-((3-hydroxypropyl)amino)oxazol-5-yl]pyrazin-2-yl}carbamic Acid tert-Butyl Ester::3-[(5-{6-[(3-chlorophenyl)amino]pyrazin-2-yl}-1,3-oxazol-2-yl)amino]propan-1-ol::pyrazine-oxazol deriv.62

SMILES: OCCCNc1ncc(o1)-c1cncc(Nc2cccc(Cl)c2)n1

InChI Key: InChIKey=YMNUEHRMMXCIPT-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 6437   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
VEGFR-2 (KDR) (Rattus norvegicus (rat))	BDBM6437 ((3-Chlorophenyl){6-[2-((3-hydroxypropyl)amino)oxaz...) Show SMILES OCCCNc1ncc(o1)-c1cncc(Nc2cccc(Cl)c2)n1 Show InChI InChI=1S/C16H16ClN5O2/c17-11-3-1-4-12(7-11)21-15-10-18-8-13(22-15)14-9-20-16(24-14)19-5-2-6-23/h1,3-4,7-10,23H,2,5-6H2,(H,19,20)(H,21,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.11E+3	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical					Assay Description The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...				J Med Chem 48: 1886-900 (2005) Article DOI: 10.1021/jm040099a BindingDB Entry DOI: 10.7270/Q2HM56NC
					More data for this Ligand-Target Pair
Cyclin-Dependent Kinase 1 (CDK1) (Homo sapiens (Human))	BDBM6437 ((3-Chlorophenyl){6-[2-((3-hydroxypropyl)amino)oxaz...) Show SMILES OCCCNc1ncc(o1)-c1cncc(Nc2cccc(Cl)c2)n1 Show InChI InChI=1S/C16H16ClN5O2/c17-11-3-1-4-12(7-11)21-15-10-18-8-13(22-15)14-9-20-16(24-14)19-5-2-6-23/h1,3-4,7-10,23H,2,5-6H2,(H,19,20)(H,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	8.0	30
Johnson & Johnson Pharmaceutical					Assay Description The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...				J Med Chem 48: 1886-900 (2005) Article DOI: 10.1021/jm040099a BindingDB Entry DOI: 10.7270/Q2HM56NC
					More data for this Ligand-Target Pair