BDBM64871 N-(6-chloranylpyridin-3-yl)-4-fluoranyl-benzamide::N-(6-chloro-3-pyridinyl)-4-fluorobenzamide::N-(6-chloro-3-pyridyl)-4-fluoro-benzamide::N-(6-chloropyridin-3-yl)-4-fluorobenzamide::ZTZ240::cid_3780776

SMILES: Fc1ccc(cc1)C(=O)Nc1ccc(Cl)nc1

InChI Key: InChIKey=URPKVELJRWKNQS-UHFFFAOYSA-N

Data: 1 IC50  1 Kd  3 EC50

PDB links: 2 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 64871   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Potassium voltage-gated channel subfamily KQT member 2 (Rattus norvegicus)	BDBM64871 (N-(6-chloranylpyridin-3-yl)-4-fluoranyl-benzamide ...) Show SMILES Fc1ccc(cc1)C(=O)Nc1ccc(Cl)nc1 Show InChI InChI=1S/C12H8ClFN2O/c13-11-6-5-10(7-15-11)16-12(17)8-1-3-9(14)4-2-8/h1-7H,(H,16,17)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid PDB UniChem Similars	PDB PCBioAssay	n/a	n/a	n/a	n/a	5.80E+3	n/a	n/a	n/a	n/a
Johns Hopkins Ion Channel Center Curated by PubChem BioAssay					Assay Description Data Source: Johns Hopkins Ion Channel Center BioAssay Type: Mode of Action, Electrophysiology Source (MLPCN Center Name): Johns Hopkins Ion Channel...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2KW5DHF
					More data for this Ligand-Target Pair				3D Structure (crystal)
Potassium voltage-gated channel subfamily KQT member 2 (Rattus norvegicus)	BDBM64871 (N-(6-chloranylpyridin-3-yl)-4-fluoranyl-benzamide ...) Show SMILES Fc1ccc(cc1)C(=O)Nc1ccc(Cl)nc1 Show InChI InChI=1S/C12H8ClFN2O/c13-11-6-5-10(7-15-11)16-12(17)8-1-3-9(14)4-2-8/h1-7H,(H,16,17)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid PDB UniChem Similars	PDB PCBioAssay	n/a	n/a	n/a	n/a	5.90E+3	n/a	n/a	n/a	n/a
Johns Hopkins Ion Channel Center Curated by PubChem BioAssay					Assay Description Data Source: Johns Hopkins Ion Channel Center BioAssay Type: Mode of Action, Electrophysiology Source (MLPCN Center Name): Johns Hopkins Ion Channel...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2Z31X37
					More data for this Ligand-Target Pair				3D Structure (crystal)
Potassium voltage-gated channel subfamily E/KQT member 1 (Homo sapiens (Human))	BDBM64871 (N-(6-chloranylpyridin-3-yl)-4-fluoranyl-benzamide ...) Show SMILES Fc1ccc(cc1)C(=O)Nc1ccc(Cl)nc1 Show InChI InChI=1S/C12H8ClFN2O/c13-11-6-5-10(7-15-11)16-12(17)8-1-3-9(14)4-2-8/h1-7H,(H,16,17)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	6.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Antagonist activity at KCNQ1/MINK expressed in CHO cells assessed as inhibition of KCl-induced 86Rb+ efflux incubated for 10 mins prior to KCl-induct...				ACS Med Chem Lett 2: 481-484 (2011) Article DOI: 10.1021/ml200053x BindingDB Entry DOI: 10.7270/Q2R49RVJ
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily KQT member 2/3 (Homo sapiens (Human))	BDBM64871 (N-(6-chloranylpyridin-3-yl)-4-fluoranyl-benzamide ...) Show SMILES Fc1ccc(cc1)C(=O)Nc1ccc(Cl)nc1 Show InChI InChI=1S/C12H8ClFN2O/c13-11-6-5-10(7-15-11)16-12(17)8-1-3-9(14)4-2-8/h1-7H,(H,16,17)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	980	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Agonist activity at KCNQ2/KCNQ3 expressed in CHO cells assessed as increase in KCl-induced 86Rb+ efflux incubated for 10 mins prior to KCl-induction ...				ACS Med Chem Lett 2: 481-484 (2011) Article DOI: 10.1021/ml200053x BindingDB Entry DOI: 10.7270/Q2R49RVJ
					More data for this Ligand-Target Pair				3D Structure (crystal)
Beta-secretase 1 (Homo sapiens (Human))	BDBM64871 (N-(6-chloranylpyridin-3-yl)-4-fluoranyl-benzamide ...) Show SMILES Fc1ccc(cc1)C(=O)Nc1ccc(Cl)nc1 Show InChI InChI=1S/C12H8ClFN2O/c13-11-6-5-10(7-15-11)16-12(17)8-1-3-9(14)4-2-8/h1-7H,(H,16,17)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid PDB UniChem Similars	PubMed	n/a	n/a	n/a	1.14E+5	n/a	n/a	n/a	n/a	n/a
Amgen, Inc. Curated by ChEMBL					Assay Description Binding affinity to BACE1 (unknown origin) by surface plasmon resonance spectroscopic analysis				J Med Chem 59: 3732-49 (2016) BindingDB Entry DOI: 10.7270/Q2RF5WXP
					More data for this Ligand-Target Pair