BDBM6538 4-[(E)-2-{3-cyano-4-[(2,4-dichloro-5-methoxyphenyl)amino]-6-methoxyquinolin-7-yl}ethenyl]-1-oxidopyridin-1-ium::ethenyl-4-phenylamino-3-quinolinecarbonitrile 20b

SMILES: COc1cc(Nc2c(cnc3cc(\C=C\c4cc[n+]([O-])cc4)c(OC)cc23)C#N)c(Cl)cc1Cl

InChI Key: InChIKey=LMEHKNIOALOSME-ONEGZZNKSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 6538   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM6538 (4-[(E)-2-{3-cyano-4-[(2,4-dichloro-5-methoxyphenyl...) Show SMILES COc1cc(Nc2c(cnc3cc(\C=C\c4cc[n+]([O-])cc4)c(OC)cc23)C#N)c(Cl)cc1Cl Show InChI InChI=1S/C25H18Cl2N4O3/c1-33-23-10-18-21(9-16(23)4-3-15-5-7-31(32)8-6-15)29-14-17(13-28)25(18)30-22-12-24(34-2)20(27)11-19(22)26/h3-12,14H,1-2H3,(H,29,30)/b4-3+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research					Assay Description Kinase assays were performed using the europium/APC detection format (LANCE, Perkin Elmer). HTRF is based on the proximity of europium cryptate (dono...				Bioorg Med Chem Lett 15: 1743-7 (2005) Article DOI: 10.1016/j.bmcl.2005.01.004 BindingDB Entry DOI: 10.7270/Q2VX0DRH
					More data for this Ligand-Target Pair