BDBM65507 CPZ analog, 1

SMILES: CC(C)CCCN1c2ccccc2Sc2ccc(Cl)cc12

InChI Key: InChIKey=IMYKKTVSQLRQPB-UHFFFAOYSA-N

Data: 1 KI  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 65507   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM65507 (CPZ analog, 1) Show SMILES CC(C)CCCN1c2ccccc2Sc2ccc(Cl)cc12 Show InChI InChI=1S/C18H20ClNS/c1-13(2)6-5-11-20-15-7-3-4-8-17(15)21-18-10-9-14(19)12-16(18)20/h3-4,7-10,12-13H,5-6,11H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	>2.50E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Michigan State University					Assay Description Human embryonic kidney (HEK-293) cells were plated in 100 mm plates and transfected with pcDNA3.1-D2R using Lipofectamine 2000 (Invitrogen; Waltham, ...				ACS Chem Biol 12: 2240-2247 (2017) Article DOI: 10.1021/acschembio.7b00489 BindingDB Entry DOI: 10.7270/Q2DV1H2F
					More data for this Ligand-Target Pair
Proteasome subunit alpha type-6 (Homo sapiens (Human))	BDBM65507 (CPZ analog, 1) Show SMILES CC(C)CCCN1c2ccccc2Sc2ccc(Cl)cc12 Show InChI InChI=1S/C18H20ClNS/c1-13(2)6-5-11-20-15-7-3-4-8-17(15)21-18-10-9-14(19)12-16(18)20/h3-4,7-10,12-13H,5-6,11H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>2.50E+4	n/a	n/a	7.5	37
Michigan State University					Assay Description Activity assays were carried out in a 200 uL reaction volume. Different concentrations of test compounds were added to a black flat/clear bottom 96-w...				ACS Chem Biol 12: 2240-2247 (2017) Article DOI: 10.1021/acschembio.7b00489 BindingDB Entry DOI: 10.7270/Q2DV1H2F
					More data for this Ligand-Target Pair