BDBM65508 CPZ analog, 2
SMILES: OS(=O)(=O)CCCCN1c2ccccc2Sc2ccc(Cl)cc12
InChI Key: InChIKey=LYNDVTVYYWZTSM-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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5-hydroxytryptamine receptor 7 (Homo sapiens (Human)) | BDBM65508 (CPZ analog, 2) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | KEGG PC cid PC sid UniChem Similars | Article PubMed | >2.50E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Michigan State University | Assay Description Human embryonic kidney (HEK-293) cells were plated in 100 mm plates and transfected with pcDNA3.1-D2R using Lipofectamine 2000 (Invitrogen; Waltham, ... | ACS Chem Biol 12: 2240-2247 (2017) Article DOI: 10.1021/acschembio.7b00489 BindingDB Entry DOI: 10.7270/Q2DV1H2F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proteasome subunit alpha type-6 (Homo sapiens (Human)) | BDBM65508 (CPZ analog, 2) | PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 6.30E+3 | n/a | n/a | 7.5 | 37 |
Michigan State University | Assay Description Activity assays were carried out in a 200 uL reaction volume. Different concentrations of test compounds were added to a black flat/clear bottom 96-w... | ACS Chem Biol 12: 2240-2247 (2017) Article DOI: 10.1021/acschembio.7b00489 BindingDB Entry DOI: 10.7270/Q2DV1H2F | |||||||||||
More data for this Ligand-Target Pair |