BDBM65518 5-Chloro-1-[(2,5-dichlorophenyl)methyl]-1H-indole-2,3-dione 3-(O-acetyloxime)::668467-91-2::LDN-57444

SMILES: CC(=O)ON=C1C(=O)N(Cc2cc(Cl)ccc2Cl)c2ccc(Cl)cc12

InChI Key: InChIKey=OPQRFPHLZZPCCH-PGMHBOJBSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 65518   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ubiquitin carboxyl-terminal hydrolase isozyme L1 (Homo sapiens (Human))	BDBM65518 (5-Chloro-1-[(2,5-dichlorophenyl)methyl]-1H-indole-...) Show SMILES CC(=O)ON=C1C(=O)N(Cc2cc(Cl)ccc2Cl)c2ccc(Cl)cc12 |w:4.3| Show InChI InChI=1S/C17H11Cl3N2O3/c1-9(23)25-21-16-13-7-12(19)3-5-15(13)22(17(16)24)8-10-6-11(18)2-4-14(10)20/h2-7H,8H2,1H3/b21-16-	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	7.5	25
University of Delaware					Assay Description Ubiquitin-7-amino-4-methylcoumarin (Ub-AMC) was generated as previously described.(7) The enzymatic reaction was conducted in fluorometric assay buff...				ACS Chem Biol 12: 2399-2407 (2017) Article DOI: 10.1021/acschembio.7b00543 BindingDB Entry DOI: 10.7270/Q21J97WD
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L5 (Homo sapiens (Human))	BDBM65518 (5-Chloro-1-[(2,5-dichlorophenyl)methyl]-1H-indole-...) Show SMILES CC(=O)ON=C1C(=O)N(Cc2cc(Cl)ccc2Cl)c2ccc(Cl)cc12 |w:4.3| Show InChI InChI=1S/C17H11Cl3N2O3/c1-9(23)25-21-16-13-7-12(19)3-5-15(13)22(17(16)24)8-10-6-11(18)2-4-14(10)20/h2-7H,8H2,1H3/b21-16-	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.62E+4	n/a	n/a	n/a	n/a	7.5	25
University of Delaware					Assay Description Ubiquitin-7-amino-4-methylcoumarin (Ub-AMC) was generated as previously described.(7) The enzymatic reaction was conducted in fluorometric assay buff...				ACS Chem Biol 12: 2399-2407 (2017) Article DOI: 10.1021/acschembio.7b00543 BindingDB Entry DOI: 10.7270/Q21J97WD
					More data for this Ligand-Target Pair
Ubiquitin C-terminal Hydrolase L3 (UCH-L3) (Homo sapiens (Human))	BDBM65518 (5-Chloro-1-[(2,5-dichlorophenyl)methyl]-1H-indole-...) Show SMILES CC(=O)ON=C1C(=O)N(Cc2cc(Cl)ccc2Cl)c2ccc(Cl)cc12 |w:4.3| Show InChI InChI=1S/C17H11Cl3N2O3/c1-9(23)25-21-16-13-7-12(19)3-5-15(13)22(17(16)24)8-10-6-11(18)2-4-14(10)20/h2-7H,8H2,1H3/b21-16-	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.41E+4	n/a	n/a	n/a	n/a	7.5	25
University of Delaware					Assay Description Ubiquitin-7-amino-4-methylcoumarin (Ub-AMC) was generated as previously described.(7) The enzymatic reaction was conducted in fluorometric assay buff...				ACS Chem Biol 12: 2399-2407 (2017) Article DOI: 10.1021/acschembio.7b00543 BindingDB Entry DOI: 10.7270/Q21J97WD
					More data for this Ligand-Target Pair