BDBM6575 (7-Methoxy-1H-2-indolyl)(1H-2-indolyl)methanone::2-(1H-indol-2-ylcarbonyl)-7-methoxy-1H-indole::Bis(1H-2-indolyl)methanone 13

SMILES: COc1cccc2cc([nH]c12)C(=O)c1cc2ccccc2[nH]1

InChI Key: InChIKey=OATAATAPIWYBRK-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 6575   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM6575 ((7-Methoxy-1H-2-indolyl)(1H-2-indolyl)methanone | ...) Show SMILES COc1cccc2cc([nH]c12)C(=O)c1cc2ccccc2[nH]1 Show InChI InChI=1S/C18H14N2O2/c1-22-16-8-4-6-12-10-15(20-17(12)16)18(21)14-9-11-5-2-3-7-13(11)19-14/h2-10,19-20H,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	7.4	22
University of Regensburg					Assay Description The cells were stimulated with PDGF (100 ng/mL) for 10 min at room temperature. Then the cell lysates were analyzed by SDS-PAGE and immunoblotting wi...				J Med Chem 45: 1002-18 (2002) Article DOI: 10.1021/jm010988n BindingDB Entry DOI: 10.7270/Q2GM85H0
					More data for this Ligand-Target Pair