BDBM6584 1H-2-Indolyl-[5-(2-(morpholin-1-yl)ethoxy)-1H-2-indolyl]-methanone::4-(2-{[2-(1H-indol-2-ylcarbonyl)-1H-indol-5-yl]oxy}ethyl)morpholine::Bis(1H-2-indolyl)methanone 42

SMILES: O=C(c1cc2ccccc2[nH]1)c1cc2cc(OCCN3CCOCC3)ccc2[nH]1

InChI Key: InChIKey=QDELNGWKLWYINZ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 6584   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM6584 (1H-2-Indolyl-[5-(2-(morpholin-1-yl)ethoxy)-1H-2-in...) Show SMILES O=C(c1cc2ccccc2[nH]1)c1cc2cc(OCCN3CCOCC3)ccc2[nH]1 Show InChI InChI=1S/C23H23N3O3/c27-23(21-14-16-3-1-2-4-19(16)24-21)22-15-17-13-18(5-6-20(17)25-22)29-12-9-26-7-10-28-11-8-26/h1-6,13-15,24-25H,7-12H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	7.4	22
University of Regensburg					Assay Description The cells were stimulated with PDGF (100 ng/mL) for 10 min at room temperature. Then the cell lysates were analyzed by SDS-PAGE and immunoblotting wi...				J Med Chem 45: 1002-18 (2002) Article DOI: 10.1021/jm010988n BindingDB Entry DOI: 10.7270/Q2GM85H0
					More data for this Ligand-Target Pair