BDBM6585 (3-{[2-(1H-indol-2-ylcarbonyl)-1H-indol-5-yl]oxy}propyl)dimethylamine::1H-2-Indolyl-[5-(3-dimethylaminopropyloxy)-1H-2-indolyl]methanone::Bis(1H-2-indolyl)methanone 43

SMILES: CN(C)CCCOc1ccc2[nH]c(cc2c1)C(=O)c1cc2ccccc2[nH]1

InChI Key: InChIKey=SXFHYOPBKFNFKX-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 6585   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM6585 ((3-{[2-(1H-indol-2-ylcarbonyl)-1H-indol-5-yl]oxy}p...) Show SMILES CN(C)CCCOc1ccc2[nH]c(cc2c1)C(=O)c1cc2ccccc2[nH]1 Show InChI InChI=1S/C22H23N3O2/c1-25(2)10-5-11-27-17-8-9-19-16(12-17)14-21(24-19)22(26)20-13-15-6-3-4-7-18(15)23-20/h3-4,6-9,12-14,23-24H,5,10-11H2,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.20E+3	n/a	n/a	n/a	n/a	7.4	22
University of Regensburg					Assay Description The cells were stimulated with PDGF (100 ng/mL) for 10 min at room temperature. Then the cell lysates were analyzed by SDS-PAGE and immunoblotting wi...				J Med Chem 45: 1002-18 (2002) Article DOI: 10.1021/jm010988n BindingDB Entry DOI: 10.7270/Q2GM85H0
					More data for this Ligand-Target Pair