BDBM6587 (2-{[2-(1H-indol-2-ylcarbonyl)-1H-indol-5-yl]oxy}ethyl)dimethylamine::1H-2-Indolyl-[5-(2-dimethylaminoethoxy)-1H-2-indolyl]-methanone::Bis(1H-2-indolyl)methanone 45

SMILES: CN(C)CCOc1ccc2[nH]c(cc2c1)C(=O)c1cc2ccccc2[nH]1

InChI Key: InChIKey=MWOGGCAYFLMOGW-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 6587   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM6587 ((2-{[2-(1H-indol-2-ylcarbonyl)-1H-indol-5-yl]oxy}e...) Show SMILES CN(C)CCOc1ccc2[nH]c(cc2c1)C(=O)c1cc2ccccc2[nH]1 Show InChI InChI=1S/C21H21N3O2/c1-24(2)9-10-26-16-7-8-18-15(11-16)13-20(23-18)21(25)19-12-14-5-3-4-6-17(14)22-19/h3-8,11-13,22-23H,9-10H2,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	800	n/a	n/a	n/a	n/a	7.4	22
University of Regensburg					Assay Description The cells were stimulated with PDGF (100 ng/mL) for 10 min at room temperature. Then the cell lysates were analyzed by SDS-PAGE and immunoblotting wi...				J Med Chem 45: 1002-18 (2002) Article DOI: 10.1021/jm010988n BindingDB Entry DOI: 10.7270/Q2GM85H0
					More data for this Ligand-Target Pair