BDBM6591 1H-2-Indolyl-[5-(2-piperidin-1-ylethoxy)-1H-2-indolyl]-methanone::2-(1H-indol-2-ylcarbonyl)-5-[2-(piperidin-1-yl)ethoxy]-1H-indole::Bis(1H-2-indolyl)methanone deriv. 49

SMILES: O=C(c1cc2ccccc2[nH]1)c1cc2cc(OCCN3CCCCC3)ccc2[nH]1

InChI Key: InChIKey=IVPTZHGWATUPFL-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 6591   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM6591 (1H-2-Indolyl-[5-(2-piperidin-1-ylethoxy)-1H-2-indo...) Show SMILES O=C(c1cc2ccccc2[nH]1)c1cc2cc(OCCN3CCCCC3)ccc2[nH]1 Show InChI InChI=1S/C24H25N3O2/c28-24(22-15-17-6-2-3-7-20(17)25-22)23-16-18-14-19(8-9-21(18)26-23)29-13-12-27-10-4-1-5-11-27/h2-3,6-9,14-16,25-26H,1,4-5,10-13H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	800	n/a	n/a	n/a	n/a	n/a	25
University of Regensburg					Assay Description The cells were stimulated with PDGF (100 ng/mL) for 10 min at room temperature. Then the cell lysates were analyzed by SDS-PAGE and immunoblotting wi...				J Med Chem 45: 1002-18 (2002) Article DOI: 10.1021/jm010988n BindingDB Entry DOI: 10.7270/Q2GM85H0
					More data for this Ligand-Target Pair