BDBM6595 2-(1H-indol-2-ylcarbonyl)-1H-indol-5-yl 2-(dimethylamino)acetate::Bis(1H-2-indolyl)methanone deriv. 53::[2-(1H-2-Indolylcarbonyl)-1H-5-indolyl]dimethylaminoethanoate
SMILES: CN(C)CC(=O)Oc1ccc2[nH]c(cc2c1)C(=O)c1cc2ccccc2[nH]1
InChI Key: InChIKey=HFEANGBCVOPJFK-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Platelet-derived growth factor receptor beta (Homo sapiens (Human)) | BDBM6595 (2-(1H-indol-2-ylcarbonyl)-1H-indol-5-yl 2-(dimethy...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | 25 |
University of Regensburg | Assay Description The cells were stimulated with PDGF (100 ng/mL) for 10 min at room temperature. Then the cell lysates were analyzed by SDS-PAGE and immunoblotting wi... | J Med Chem 45: 1002-18 (2002) Article DOI: 10.1021/jm010988n BindingDB Entry DOI: 10.7270/Q2GM85H0 | |||||||||||
More data for this Ligand-Target Pair |