BDBM65974 3-[(5E)-5-[4-(4-chlorobenzyl)oxy-3-methoxy-benzylidene]-4-keto-2-thioxo-thiazolidin-3-yl]benzoic acid::3-[(5E)-5-[[4-[(4-chlorophenyl)methoxy]-3-methoxy-phenyl]methylidene]-4-oxidanylidene-2-sulfanylidene-1,3-thiazolidin-3-yl]benzoic acid::3-[(5E)-5-[[4-[(4-chlorophenyl)methoxy]-3-methoxyphenyl]methylidene]-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]benzoic acid::3-[(5E)-5-[[4-[(4-chlorophenyl)methoxy]-3-methoxyphenyl]methylidene]-4-oxo-2-sulfanylidene-3-thiazolidinyl]benzoic acid::MLS-0435625.0001::cid_16466007

SMILES: COc1cc(\C=C2\SC(=S)N(C2=O)c2cccc(c2)C(O)=O)ccc1OCc1ccc(Cl)cc1

InChI Key: InChIKey=GHKVGXGHSJFEEO-WSDLNYQXSA-N

Data: 6 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 65974   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP (Homo sapiens (Human))	BDBM65974 (3-[(5E)-5-[4-(4-chlorobenzyl)oxy-3-methoxy-benzyli...) Show SMILES COc1cc(\C=C2\SC(=S)N(C2=O)c2cccc(c2)C(O)=O)ccc1OCc1ccc(Cl)cc1 Show InChI InChI=1S/C25H18ClNO5S2/c1-31-21-11-16(7-10-20(21)32-14-15-5-8-18(26)9-6-15)12-22-23(28)27(25(33)34-22)19-4-2-3-17(13-19)24(29)30/h2-13H,14H2,1H3,(H,29,30)/b22-12+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	3.68E+3	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute(SBMRI, San Diego, CA...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2B56H6M
					More data for this Ligand-Target Pair
Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP (Homo sapiens (Human))	BDBM65974 (3-[(5E)-5-[4-(4-chlorobenzyl)oxy-3-methoxy-benzyli...) Show SMILES COc1cc(\C=C2\SC(=S)N(C2=O)c2cccc(c2)C(O)=O)ccc1OCc1ccc(Cl)cc1 Show InChI InChI=1S/C25H18ClNO5S2/c1-31-21-11-16(7-10-20(21)32-14-15-5-8-18(26)9-6-15)12-22-23(28)27(25(33)34-22)19-4-2-3-17(13-19)24(29)30/h2-13H,14H2,1H3,(H,29,30)/b22-12+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	4.04E+3	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q26H4FVR
					More data for this Ligand-Target Pair
tyrosine-protein phosphatase non-receptor type 12 isoform 2 (Homo sapiens (Human))	BDBM65974 (3-[(5E)-5-[4-(4-chlorobenzyl)oxy-3-methoxy-benzyli...) Show SMILES COc1cc(\C=C2\SC(=S)N(C2=O)c2cccc(c2)C(O)=O)ccc1OCc1ccc(Cl)cc1 Show InChI InChI=1S/C25H18ClNO5S2/c1-31-21-11-16(7-10-20(21)32-14-15-5-8-18(26)9-6-15)12-22-23(28)27(25(33)34-22)19-4-2-3-17(13-19)24(29)30/h2-13H,14H2,1H3,(H,29,30)/b22-12+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	953	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q28G8J5T
					More data for this Ligand-Target Pair
Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP (Homo sapiens (Human))	BDBM65974 (3-[(5E)-5-[4-(4-chlorobenzyl)oxy-3-methoxy-benzyli...) Show SMILES COc1cc(\C=C2\SC(=S)N(C2=O)c2cccc(c2)C(O)=O)ccc1OCc1ccc(Cl)cc1 Show InChI InChI=1S/C25H18ClNO5S2/c1-31-21-11-16(7-10-20(21)32-14-15-5-8-18(26)9-6-15)12-22-23(28)27(25(33)34-22)19-4-2-3-17(13-19)24(29)30/h2-13H,14H2,1H3,(H,29,30)/b22-12+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	3.49E+3	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute(SBMRI, San Diego, CA...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2M9073J
					More data for this Ligand-Target Pair
Hematopoietic protein-tyrosine phosphatase (HEPTP) (Homo sapiens (Human))	BDBM65974 (3-[(5E)-5-[4-(4-chlorobenzyl)oxy-3-methoxy-benzyli...) Show SMILES COc1cc(\C=C2\SC(=S)N(C2=O)c2cccc(c2)C(O)=O)ccc1OCc1ccc(Cl)cc1 Show InChI InChI=1S/C25H18ClNO5S2/c1-31-21-11-16(7-10-20(21)32-14-15-5-8-18(26)9-6-15)12-22-23(28)27(25(33)34-22)19-4-2-3-17(13-19)24(29)30/h2-13H,14H2,1H3,(H,29,30)/b22-12+	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	394	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2BR8QNJ
					More data for this Ligand-Target Pair
Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP (Homo sapiens (Human))	BDBM65974 (3-[(5E)-5-[4-(4-chlorobenzyl)oxy-3-methoxy-benzyli...) Show SMILES COc1cc(\C=C2\SC(=S)N(C2=O)c2cccc(c2)C(O)=O)ccc1OCc1ccc(Cl)cc1 Show InChI InChI=1S/C25H18ClNO5S2/c1-31-21-11-16(7-10-20(21)32-14-15-5-8-18(26)9-6-15)12-22-23(28)27(25(33)34-22)19-4-2-3-17(13-19)24(29)30/h2-13H,14H2,1H3,(H,29,30)/b22-12+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	3.06E+3	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2QZ28FP
					More data for this Ligand-Target Pair