new BindingDB logo
myBDB logout

BDBM65986 2-(3-bromophenyl)-4-quinolinecarboxylic acid [2-[4-[2-furanyl(oxo)methyl]-1-piperazinyl]-2-oxoethyl] ester::2-(3-bromophenyl)cinchoninic acid [2-[4-(2-furoyl)piperazino]-2-keto-ethyl] ester::MLS000564139::SMR000151689::[2-[4-(furan-2-carbonyl)piperazin-1-yl]-2-oxoethyl] 2-(3-bromophenyl)quinoline-4-carboxylate::[2-[4-(furan-2-ylcarbonyl)piperazin-1-yl]-2-oxidanylidene-ethyl] 2-(3-bromophenyl)quinoline-4-carboxylate::cid_2391688

SMILES: Brc1cccc(c1)-c1cc(C(=O)OCC(=O)N2CCN(CC2)C(=O)c2ccco2)c2ccccc2n1

InChI Key: InChIKey=KVOWJCJQHBKKLH-UHFFFAOYSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 65986   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
RPL19A


(Saccharomyces cerevisiae)
BDBM65986
PNG
(2-(3-bromophenyl)-4-quinolinecarboxylic acid [2-[4...)
Show SMILES Brc1cccc(c1)-c1cc(C(=O)OCC(=O)N2CCN(CC2)C(=O)c2ccco2)c2ccccc2n1
Show InChI InChI=1S/C27H22BrN3O5/c28-19-6-3-5-18(15-19)23-16-21(20-7-1-2-8-22(20)29-23)27(34)36-17-25(32)30-10-12-31(13-11-30)26(33)24-9-4-14-35-24/h1-9,14-16H,10-13,17H2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem
Article
PCBioAssay
n/an/an/an/a 3.18E+3n/an/an/an/a



NMMLSC

Curated by PubChem BioAssay


Assay Description
University of New Mexico Assay Overview: Assay Support: 1R03 MH086450-01 Project Title: Chemical Screen of TOR pathway GFP fusion proteins in S. ...


PubChem Bioassay (2010)


Article DOI: 10.1021/bi4005396
BindingDB Entry DOI: 10.7270/Q2JQ0ZGP
More data for this
Ligand-Target Pair
Agp1p


(Saccharomyces cerevisiae S288c)
BDBM65986
PNG
(2-(3-bromophenyl)-4-quinolinecarboxylic acid [2-[4...)
Show SMILES Brc1cccc(c1)-c1cc(C(=O)OCC(=O)N2CCN(CC2)C(=O)c2ccco2)c2ccccc2n1
Show InChI InChI=1S/C27H22BrN3O5/c28-19-6-3-5-18(15-19)23-16-21(20-7-1-2-8-22(20)29-23)27(34)36-17-25(32)30-10-12-31(13-11-30)26(33)24-9-4-14-35-24/h1-9,14-16H,10-13,17H2
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem
Article
PCBioAssay
n/an/an/an/a 2.81E+3n/an/an/an/a



NMMLSC

Curated by PubChem BioAssay


Assay Description
University of New Mexico Assay Overview: Assay Support: 1R03 MH086450-01 Project Title: Chemical Screen of TOR pathway GFP fusion proteins in S. ...


PubChem Bioassay (2010)


Article DOI: 10.1038/nchembio.1603
BindingDB Entry DOI: 10.7270/Q29885GJ
More data for this
Ligand-Target Pair