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BDBM65990 3-[2,5-bis(oxidanylidene)pyrrol-1-yl]-N-(2,4-dichlorophenyl)benzamide::MLS000572761::N-(2,4-dichlorophenyl)-3-(2,5-dioxo-1-pyrrolyl)benzamide::N-(2,4-dichlorophenyl)-3-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)benzamide::N-(2,4-dichlorophenyl)-3-(2,5-dioxopyrrol-1-yl)benzamide::N-(2,4-dichlorophenyl)-3-maleimido-benzamide::SMR000194626::cid_2275069

SMILES: Clc1ccc(NC(=O)c2cccc(c2)N2C(=O)C=CC2=O)c(Cl)c1

InChI Key: InChIKey=VXILOMWTKHSQQQ-UHFFFAOYSA-N

Data: 3 IC50  3 EC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 65990   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
RPL19A


(Saccharomyces cerevisiae)
BDBM65990
PNG
(3-[2,5-bis(oxidanylidene)pyrrol-1-yl]-N-(2,4-dichl...)
Show SMILES Clc1ccc(NC(=O)c2cccc(c2)N2C(=O)C=CC2=O)c(Cl)c1 |c:18|
Show InChI InChI=1S/C17H10Cl2N2O3/c18-11-4-5-14(13(19)9-11)20-17(24)10-2-1-3-12(8-10)21-15(22)6-7-16(21)23/h1-9H,(H,20,24)
PDB
MMDB

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UniProtKB/SwissProt

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UniChem
Article
PCBioAssay
n/an/an/an/a 9.64E+3n/an/an/an/a



NMMLSC

Curated by PubChem BioAssay


Assay Description
University of New Mexico Assay Overview: Assay Support: 1R03 MH086450-01 Project Title: Chemical Screen of TOR pathway GFP fusion proteins in S. ...


PubChem Bioassay (2010)


Article DOI: 10.1021/bi4005396
BindingDB Entry DOI: 10.7270/Q2JQ0ZGP
More data for this
Ligand-Target Pair
LAP4


(Saccharomyces cerevisiae)
BDBM65990
PNG
(3-[2,5-bis(oxidanylidene)pyrrol-1-yl]-N-(2,4-dichl...)
Show SMILES Clc1ccc(NC(=O)c2cccc(c2)N2C(=O)C=CC2=O)c(Cl)c1 |c:18|
Show InChI InChI=1S/C17H10Cl2N2O3/c18-11-4-5-14(13(19)9-11)20-17(24)10-2-1-3-12(8-10)21-15(22)6-7-16(21)23/h1-9H,(H,20,24)
PDB

KEGG

UniProtKB/SwissProt

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UniChem
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n/an/an/an/a 3.92E+3n/an/an/an/a



NMMLSC

Curated by PubChem BioAssay


Assay Description
University of New Mexico Assay Overview: Assay Support: 1R03 MH086450-01 Project Title: Chemical Screen of TOR pathway GFP fusion proteins in S. ...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q21R6P02
More data for this
Ligand-Target Pair
endothelial PAS domain-containing protein 1


(Homo sapiens (Human))
BDBM65990
PNG
(3-[2,5-bis(oxidanylidene)pyrrol-1-yl]-N-(2,4-dichl...)
Show SMILES Clc1ccc(NC(=O)c2cccc(c2)N2C(=O)C=CC2=O)c(Cl)c1 |c:18|
Show InChI InChI=1S/C17H10Cl2N2O3/c18-11-4-5-14(13(19)9-11)20-17(24)10-2-1-3-12(8-10)21-15(22)6-7-16(21)23/h1-9H,(H,20,24)
PDB
MMDB

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antibodypedia
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n/an/a 8.10E+3n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay




PubChem Bioassay (2012)


BindingDB Entry DOI: 10.7270/Q2WS8RVZ
More data for this
Ligand-Target Pair
DNA dC->dU-editing enzyme APOBEC-3G


(Homo sapiens (Human))
BDBM65990
PNG
(3-[2,5-bis(oxidanylidene)pyrrol-1-yl]-N-(2,4-dichl...)
Show SMILES Clc1ccc(NC(=O)c2cccc(c2)N2C(=O)C=CC2=O)c(Cl)c1 |c:18|
Show InChI InChI=1S/C17H10Cl2N2O3/c18-11-4-5-14(13(19)9-11)20-17(24)10-2-1-3-12(8-10)21-15(22)6-7-16(21)23/h1-9H,(H,20,24)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
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UniChem
PCBioAssay
n/an/a 1.38E+4n/an/an/an/an/a25



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...


PubChem Bioassay (2011)


BindingDB Entry DOI: 10.7270/Q2HQ3XD6
More data for this
Ligand-Target Pair
probable DNA dC->dU-editing enzyme APOBEC-3A


(Homo sapiens (Human))
BDBM65990
PNG
(3-[2,5-bis(oxidanylidene)pyrrol-1-yl]-N-(2,4-dichl...)
Show SMILES Clc1ccc(NC(=O)c2cccc(c2)N2C(=O)C=CC2=O)c(Cl)c1 |c:18|
Show InChI InChI=1S/C17H10Cl2N2O3/c18-11-4-5-14(13(19)9-11)20-17(24)10-2-1-3-12(8-10)21-15(22)6-7-16(21)23/h1-9H,(H,20,24)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
PCBioAssay
n/an/a>1.00E+5n/an/an/an/an/a25



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...


PubChem Bioassay (2011)


BindingDB Entry DOI: 10.7270/Q2CZ35ND
More data for this
Ligand-Target Pair
Bcl-2-like protein 11


(Homo sapiens (Human))
BDBM65990
PNG
(3-[2,5-bis(oxidanylidene)pyrrol-1-yl]-N-(2,4-dichl...)
Show SMILES Clc1ccc(NC(=O)c2cccc(c2)N2C(=O)C=CC2=O)c(Cl)c1 |c:18|
Show InChI InChI=1S/C17H10Cl2N2O3/c18-11-4-5-14(13(19)9-11)20-17(24)10-2-1-3-12(8-10)21-15(22)6-7-16(21)23/h1-9H,(H,20,24)
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n/an/an/an/a>3.50E+5n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q24J0CKJ
More data for this
Ligand-Target Pair