BDBM6606 2-(1H-indol-2-ylcarbonyl)-1H-indol-5-yl 3,4,5-trimethoxybenzoate::Bis(1H-2-indolyl)methanone deriv. 64::[2-(1H-2-Indolylcarbonyl)-1H-5-indolyl]-3,4,5-trimethoxybenzoate

SMILES: COc1cc(cc(OC)c1OC)C(=O)Oc1ccc2[nH]c(cc2c1)C(=O)c1cc2ccccc2[nH]1

InChI Key: InChIKey=HIQHTLZZJVBOPI-UHFFFAOYSA-N

Data: 1 IC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 6606   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM6606 (2-(1H-indol-2-ylcarbonyl)-1H-indol-5-yl 3,4,5-trim...) Show SMILES COc1cc(cc(OC)c1OC)C(=O)Oc1ccc2[nH]c(cc2c1)C(=O)c1cc2ccccc2[nH]1 Show InChI InChI=1S/C27H22N2O6/c1-32-23-13-17(14-24(33-2)26(23)34-3)27(31)35-18-8-9-20-16(10-18)12-22(29-20)25(30)21-11-15-6-4-5-7-19(15)28-21/h4-14,28-29H,1-3H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.10E+3	n/a	n/a	n/a	n/a	n/a	25
University of Regensburg					Assay Description The cells were stimulated with PDGF (100 ng/mL) for 10 min at room temperature. Then the cell lysates were analyzed by SDS-PAGE and immunoblotting wi...				J Med Chem 45: 1002-18 (2002) Article DOI: 10.1021/jm010988n BindingDB Entry DOI: 10.7270/Q2GM85H0
					More data for this Ligand-Target Pair