BDBM6614 2-(1H-indol-2-ylcarbonyl)-1H-indol-5-yl pyridine-3-carboxylate::Bis(1H-2-indolyl)methanone deriv. 72::[2-(1H-2-Indolylcarbonyl)-1H-5-indolyl]-3-pyridinecarboxylate

SMILES: O=C(Oc1ccc2[nH]c(cc2c1)C(=O)c1cc2ccccc2[nH]1)c1cccnc1

InChI Key: InChIKey=SGZMABKXCSXQTM-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 6614   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM6614 (2-(1H-indol-2-ylcarbonyl)-1H-indol-5-yl pyridine-3...) Show SMILES O=C(Oc1ccc2[nH]c(cc2c1)C(=O)c1cc2ccccc2[nH]1)c1cccnc1 Show InChI InChI=1S/C23H15N3O3/c27-22(20-11-14-4-1-2-6-18(14)25-20)21-12-16-10-17(7-8-19(16)26-21)29-23(28)15-5-3-9-24-13-15/h1-13,25-26H	PDB MMDB NCI pathway Reactome pathway KEGG B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	25
University of Regensburg					Assay Description The cells were stimulated with PDGF (100 ng/mL) for 10 min at room temperature. Then the cell lysates were analyzed by SDS-PAGE and immunoblotting wi...				J Med Chem 45: 1002-18 (2002) Article DOI: 10.1021/jm010988n BindingDB Entry DOI: 10.7270/Q2GM85H0
					More data for this Ligand-Target Pair