BDBM6617 2-(1H-indol-2-ylcarbonyl)-1H-indol-5-yl 3-phenoxybenzoate::Bis(1H-2-indolyl)methanone deriv. 75::[2-(1H-2-Indolylcarbonyl)-1H-5-indolyl]-3-phenoxybenzoate

SMILES: O=C(Oc1ccc2[nH]c(cc2c1)C(=O)c1cc2ccccc2[nH]1)c1cccc(Oc2ccccc2)c1

InChI Key: InChIKey=SESFCAKZYAECOF-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 6617   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM6617 (2-(1H-indol-2-ylcarbonyl)-1H-indol-5-yl 3-phenoxyb...) Show SMILES O=C(Oc1ccc2[nH]c(cc2c1)C(=O)c1cc2ccccc2[nH]1)c1cccc(Oc2ccccc2)c1 Show InChI InChI=1S/C30H20N2O4/c33-29(27-17-19-7-4-5-12-25(19)31-27)28-18-21-16-24(13-14-26(21)32-28)36-30(34)20-8-6-11-23(15-20)35-22-9-2-1-3-10-22/h1-18,31-32H	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	25
University of Regensburg					Assay Description The cells were stimulated with PDGF (100 ng/mL) for 10 min at room temperature. Then the cell lysates were analyzed by SDS-PAGE and immunoblotting wi...				J Med Chem 45: 1002-18 (2002) Article DOI: 10.1021/jm010988n BindingDB Entry DOI: 10.7270/Q2GM85H0
					More data for this Ligand-Target Pair