BDBM66190 2-amino-6-(dicyanomethylene)-4-phenyl-1H-pyridine-3,5-dicarbonitrile::2-amino-6-(dicyanomethylidene)-4-phenyl-1H-pyridine-3,5-dicarbonitrile::2-azanyl-6-(dicyanomethylidene)-4-phenyl-1H-pyridine-3,5-dicarbonitrile::MLS001163959::SMR000539348::cid_910973

SMILES: Nc1nc(C(C#N)C#N)c(C#N)c(-c2ccccc2)c1C#N

InChI Key: InChIKey=YOKGAZCODZPKKU-UHFFFAOYSA-N

Data: 4 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 66190   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
photoreceptor-specific nuclear receptor (Homo sapiens (Human))	BDBM66190 (2-amino-6-(dicyanomethylene)-4-phenyl-1H-pyridine-...) Show SMILES Nc1nc(C(C#N)C#N)c(C#N)c(-c2ccccc2)c1C#N Show InChI InChI=1S/C16H8N6/c17-6-11(7-18)15-12(8-19)14(10-4-2-1-3-5-10)13(9-20)16(21)22-15/h1-5,11H,(H2,21,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	8.41E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay					Assay Description Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: The Scripps Research Institute, TSRI Assay Provide...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2D21W22
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM66190 (2-amino-6-(dicyanomethylene)-4-phenyl-1H-pyridine-...) Show SMILES Nc1nc(C(C#N)C#N)c(C#N)c(-c2ccccc2)c1C#N Show InChI InChI=1S/C16H8N6/c17-6-11(7-18)15-12(8-19)14(10-4-2-1-3-5-10)13(9-20)16(21)22-15/h1-5,11H,(H2,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	1.92E+4	n/a	n/a	n/a	n/a
Broad Institute Curated by PubChem BioAssay					Assay Description Keywords: GSK3beta, dose response, kinase, inhibition, HTS Assay Overview: The glycogen synthase kinase-3 beta (GSK-3b) is a known master regulator f...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2TX3CTT
					More data for this Ligand-Target Pair
tyrosyl-DNA phosphodiesterase 2 (Homo sapiens (Human))	BDBM66190 (2-amino-6-(dicyanomethylene)-4-phenyl-1H-pyridine-...) Show SMILES Nc1nc(C(C#N)C#N)c(C#N)c(-c2ccccc2)c1C#N Show InChI InChI=1S/C16H8N6/c17-6-11(7-18)15-12(8-19)14(10-4-2-1-3-5-10)13(9-20)16(21)22-15/h1-5,11H,(H2,21,22)	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	1.28E+5	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay					Assay Description Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institute (TS...				PubChem Bioassay (2014) BindingDB Entry DOI: 10.7270/Q2WS8RXV
					More data for this Ligand-Target Pair
Prion protein (Homo sapiens (Human))	BDBM66190 (2-amino-6-(dicyanomethylene)-4-phenyl-1H-pyridine-...) Show SMILES Nc1nc(C(C#N)C#N)c(C#N)c(-c2ccccc2)c1C#N Show InChI InChI=1S/C16H8N6/c17-6-11(7-18)15-12(8-19)14(10-4-2-1-3-5-10)13(9-20)16(21)22-15/h1-5,11H,(H2,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	1.92E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay					Assay Description Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...				PubChem Bioassay (2014) BindingDB Entry DOI: 10.7270/Q2HM573M
					More data for this Ligand-Target Pair
nuclear receptor corepressor 2 isoform 2 (Homo sapiens (Human))	BDBM66190 (2-amino-6-(dicyanomethylene)-4-phenyl-1H-pyridine-...) Show SMILES Nc1nc(C(C#N)C#N)c(C#N)c(-c2ccccc2)c1C#N Show InChI InChI=1S/C16H8N6/c17-6-11(7-18)15-12(8-19)14(10-4-2-1-3-5-10)13(9-20)16(21)22-15/h1-5,11H,(H2,21,22)	PDB MMDB B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	3.22E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay					Assay Description Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: The Scripps Research Institute, TSRI Assay Provide...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q28914BQ
					More data for this Ligand-Target Pair